| 摘要: |
| ［摘要］ 目的 比较莫沙必利与多潘立酮治疗餐后不适综合征(PDS)的疗效。方法 将58例符合罗马ⅢPDS诊断标准的患者按入院先后半随机分为A组30例（莫沙必利片剂5 mg，3次/d，餐前服用）,B组28例（多潘立酮片10 mg，3次/d，餐前服用），疗程28 d。疗程结束后观察对比两种药物的疗效及不良反应。结果 A组的总有效率为93.3%，B组总有效率为67.9%，两组比较差异有统计学意义（P<0.05）。两组药物不良反应轻微。结论 莫沙必利与多潘立酮治疗PDS疗效均较好，不良反应轻微，但总体疗效以莫沙必利为佳。 |
| 关键词: 餐后不适综合征 莫沙必利 多潘立酮 临床观察 |
| DOI：10.3969/j.issn.1674-3806.2013.10.14 |
| 分类号:R 57 |
| 基金项目: |
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| Comparison of clinical curative effects between mosapride and domperidone in treating postprandial discomfort syndrome |
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CHEN Zhi-jun, HUANG Zi-cheng, LIN Jin-gui
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Department of Internal Medicine, Nanqiao Hospital of Nanan, Fujian 362311, China
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| Abstract: |
| ［Abstract］ Objective To compare the therapeutic effects between mosapride and domperidone in the treatment of postprandial discomfort syndrome(PDS).Methods Fifty-eight cases of PDS according to RomeⅢ PDS diagnostic criteria were randomly assigned into two groups according to admission order. In the A group,30 cases patients were treated with mosapride tablets:5 mg 3 times daily, taken before meals, in the B group, 28 patients were treated with domperidone tablets: 10 mg, 3 times daily, taken before meals, the course were 28 days. After the end of treatment,the efficacy and adverse drug reaction were compared between two groups.Results The total effective rate in the A group was 93.3% and the total effective rate in the B group was 67.9%.There was a statistically significant difference in total effective rate between two groups(P<0.05). There was minor adverse drug reactions in two groups.Conclusion The therapeutic effects of mosapride and domperidone in treating PDS are good with minor adverse reactions. But mosapride is superior to domperidone in the total effective rate. |
| Key words: Postprandial discomfort syndrome Mosapride Domperidone Clinical observation |
