| 摘要: |
| ［摘要］ 目的 分析铜绿假单胞菌对常用抗菌药物的耐药性,以指导临床对铜绿假单胞菌的合理用药。方法 采用湖南天地人公司生产的TDR.200B细菌分析系统对临床标本中分离出的铜绿假单胞菌进行药敏试验，分析我院2010-02～2012-02分离的113株铜绿假单胞菌的耐药性。结果 铜绿假单胞菌对19种常用抗菌药物的耐药率以亚胺培南最低（10.6%）,其次为阿米卡星（12.4%）；其中敏感株7株（6.2%），多重耐药株25株（22.1%）,泛耐药株8株（7.1%）,其余耐药株73株（64.6%）。结论 铜绿假单胞菌对19种常用抗菌药物存在不同的耐药性,应加强铜绿假单胞菌的耐药性监测,为临床合理选用抗菌药物提供依据。同时应对多重和泛耐药铜绿假单胞菌采取有效的预防措施，避免多重和泛耐药株的暴发流行。 |
| 关键词: 铜绿假单胞菌 耐药性 多重耐药株 泛耐药株 |
| DOI：10.3969/j.issn.1674-3806.2013.11.20 |
| 分类号:R 37 |
| 基金项目: |
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| Analysis of drug resistance of 113 strains of pseudomonas aeruginosa |
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ZHOU Jia-shun
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Department of Clinical Laboratories， Lingshan Hospital of Traditional Chinese Medicine, Guangxi 535400，China
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| Abstract: |
| ［Abstract］ Objective To analyze the drug resistance of pseudomonas aeruginosa, and to guide clinical rational drug use of pseudomonas aeruginosa.Methods The Hunan TDR.200B was used for testing the susceptibility of pseudomonas aeruginosa isolated from clinical specimens, and analysis of drug resistance of 113 strains of pseudomonas aeruginosa were performed from February 2010 to February 2012.Results In the 19 general kinds of antimicrobial drugs the resistance rate of pseudomonas aeruginosa to imipenem was lowest(10.6%),followed by amikacin(12.4%). Among them 7 strains were susceptible strains, accounted for 6.2%; 25 strains were multi-drug resistant strains, accounted for 22.1%; 8 strains were pan-drug resistant strains, accounted for 7.1%;the rest of resistant strains, 73 strains, accounted for 64.6%.Conclusion Pseudomonas aeruginosa have different resistance to 19 kinds of antimicrobial agents, so it is necessary to strengthen the monitoring of drug resistance of pseudomonas aeruginosa, provide the basis for rational use of clinical antibiotics. At the same time,it is necessary to take effective preventive measures for multiple and pan-drug resistant pseudomonas aeruginosa,to avoid the outbreak of multiple and pan-resistant strains. |
| Key words: Pseudomonas aeruginosa Drug resistance Multi-drug resistant strains Pan-drug resistant strains |
