| 摘要: |
| ［摘要］ 目的 分析原发性甲状腺功能减退（原发性甲减）合并脑梗死患者的幽门螺旋杆菌(Hp)感染情况，并探讨其可能的作用机制。方法 选择82例原发性甲减合并脑梗死患者，根据Hp检测结果分成Hp阳性组（50例）和Hp阴性组（32例），对脑梗死的一些高危因素进行对比分析。结果 Hp阳性组的C-反应蛋白（CRP）、甘油三酯（TG）、低密度脂蛋白胆固醇（LDL-C）高于Hp阴性组（P<0.01），而高密度脂蛋白胆固醇（HDL-C）低于Hp阴性组（P<0.05）。结论 Hp感染可能是原发性甲减患者发生脑梗死的危险因素之一。 |
| 关键词: 原发性甲状腺功能减退 脑梗死 幽门螺旋杆菌感染 |
| DOI：10.3969/j.issn.1674-3806.2014.01.11 |
| 分类号:R 581 |
| 基金项目: |
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| Analysis on helicobacter pylori infection of patients with primary hypothyroidism combined with cerebral infarction |
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DENG Xiao-feng, HE Cun-lan
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Department of Endocrinology,the First People′s Hospital of Qujing,Yunnan 655000,China
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| Abstract: |
| ［Abstract］ Objective To evaluate the relationship of helicobacter pylori(Hp) infection with cerebral infarction in patients with primary hypothyroidism and analyze of the possible mechanism.Methods Eighty-two cases with primary hypothyroidism were divided into two groups according to the results of Hp:Positive Hp group(n=50) and negative Hp group(n=32).The high risk factor of cerebral infarction were detected.Results Positive Hp group showed higher C-response protein(CRP) and TG and LDL-C than the negative Hp group（P<0.01）, but lower HDL-C than the negative Hp group（P<0.05）.Conclusion Results showed that Hp infection may be a risk factor of cerebral infarction in primary hypothyroidism. |
| Key words: Primary hypothyroidism Cerebral infarction Helicobacter pylori infection |
