| 摘要: |
| ［摘要］ 目的 探讨复发急性格林-巴利综合征（GBS）的临床特点。方法 选择收治的3例复发GBS的患者（均符合Asbury 1990年诊断标准），分析其诱因、发病过程、临床表现、肌电生理检查、脑脊液检查、治疗及预后等。结果 经治疗3例中1例3个月恢复正常，1例5个月恢复正常，1例遗留肢体肌力减弱。结论 复发GBS有发病急、进展快、病程长及病情重等特点，治疗目前仍以免疫球蛋白及血浆置换等方法为主，临床预后相对较好，但对于反复发作的GBS，亦可以遗留严重的神经功能损害。 |
| 关键词: 格林-巴利综合征 脱髓鞘 |
| DOI：10.3969/j.issn.1674-3806.2014.01.17 |
| 分类号:R 74 |
| 基金项目: |
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| Clinical analysis of recurrent Guillain-Barre syndrome |
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ZHAO Yan,FU Zhi-xin,ZHANG Jin-hua
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Department of Neurology, the Central Hospital of Kaifeng City,Henan 475000,China
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| Abstract: |
| ［Abstract］ Objective To explore the clinical feature of recurrent Guillain-Barre syndrome(GBS).Methods The predisposition, pathogenetic process, clinical manifestations, electrophysiologic examination, cerebrospinal fluid examination, therapeutic process and prognosis were analyzed in 3 patients with recurrent GBS in accord with diagnostic criteria of Asbury in 1990.Results Complete recovery was abstained in one patient 3 months after treatment, and in one patient 5 months after treatment, and mild decrease of limbs muscle strength was left in one patient.Conclusion Recurrent GBS was characterized by acute onset,rapid deterioration,long and critical course. The main treatment included intravenous immunoglobulin or plasma exchange.Clinical prognosis was relatively good.But severe nerve function damage maybe leaved in the patients with repeated relapse of GBS. |
| Key words: Guillain-Barre syndrome(GBS) Demyelination |
