摘要: |
[摘要] 子宫内膜异位症(endometriosis,EMS)是妇科最常见的疾病之一,发病率呈逐年上升趋势,是引起痛经、月经不调、不孕症等的重要原因,严重影响妇女的身心健康和生活质量。目前对其机制包括核转录因子κB(NF-κBp65)在EMS中作用机制进行了不少研究,但仍未完全阐明且缺乏有效的治疗方法。该文对NF-κBp65在EMS中作用机制进行综述,以期为NF-κBp65的研究及应用上升到新的领域。 |
关键词: 子宫内膜异位症 NF-κBp65 信号通路 |
DOI:10.3969/j.issn.1674-3806.2014.08.32 |
分类号:R 711 |
基金项目:国家自然科学基金资助项目(编号:81260548) |
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Research progress on the relation between NF-κBp65 signal pathway and endometriosis |
HUANG Xiao-feng, LI Wei-hong
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Guangxi University of Traditional Chinese Medicine,Nanning 530001,China
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Abstract: |
[Abstract] Endometriosis(EMS) is one of the commonest gynecologic diseases with increasing incidence rate year by year. It causes dysmenorrheal, abnormal uterine bleeding, infertility and so on. These disease seriously affect women′s health and life quality. Many researches have been made about its mechanism, especially, the mechanism of NF-κBp65 in endometriosis. However, the mechanism of NF-κBp65 has not been fully elucidated and endometriosis is lack of effective treatment methods. Here we summarize the mechanisms of NF-κBp65 in endometriosis, which is helpful for promoting its research and application. |
Key words: Endometriosis(EMS) NF-κBp65 Signal pathway |