引用本文:梁大华,秦志强,韦海明,莫祥兰.肺真菌病59例病原学和影像学分析[J].中国临床新医学,2014,7(12):1127-1129.
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肺真菌病59例病原学和影像学分析
梁大华,秦志强,韦海明,莫祥兰
530021 南宁,广西壮族自治区人民医院呼吸内科(梁大华,秦志强),病理科(韦海明,莫祥兰)
摘要:
[摘要] 目的 探讨肺真菌病的病原学分布和影像学特征。方法 收集肺真菌病59例,均经支气管镜、经皮肺穿刺活检或手术切除送病理学确诊,分析其病原学分布和影像学特征。结果 59例病理学确诊肺真菌病患者中,肺曲霉病24例(40.7%),肺隐球菌病24例(40.7%),肺毛霉病5例(8.5%),肺念珠菌病4例(6.8%),组织胞浆菌病2例(3.4%),合并放线菌肺炎1例(1.7%)。胸部影像学改变包括肺部肿块23例(39.0%),渗出性病变23例(39.0%),结节8例(13.6%),支气管肿物3例(5.1%),空洞病变1例(1.7%),弥漫性病变1例(1.7%)。误诊为肺炎12例(20.3%),肺结核7例(11.9%),肺癌4例(6.8%)。结论 病理学确诊的肺真菌病以肺曲霉病和肺隐球菌病为多见,影像学表现主要以肺部肿块影和渗出性病变为主。肺真菌病影像学表现多种多样、缺乏特征性,诊断应尽早取得病理学依据。
关键词:  肺真菌病  肺曲霉病  肺隐球菌病
DOI:10.3969/j.issn.1674-3806.2014.12.10
分类号:R 44
基金项目:
Etiology and imaging analysis of 59 patients with pulmonary fungal disease
LIANG Da-hua, QIN Zhi-qiang, WEI Hai-ming, et al.
Department of Respiratory Disease, the People′s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China
Abstract:
[Abstract] Objective To observe the etiological distribution and imaging features of pulmonary fungal disease that was diagnosed by pathology in the People′s Hospital of Guangxi Zhuang Autonomous Region.Methods Fifty-night patients with pulmonary fungal disease were collected and analyzed in the People′s Hospital of Guangxi Zhuang Autonomous Region from June 2004 to March 2013.The diagnosis of all the patients was confirmed by pathological examination,of lung or bronchi tissue that was obtained by bronchoscope, percutaneous lung puncture biopsy or operation.Results Of the 59 patients who were diagnosed having pulmonary fungal disease by pathology, 24 patients(40.7%) suffered from pulmonary aspergillosis,24 patients(40.7%) suffered from pulmonary cryptococcosis, 5 patients(8.5%) suffered from pulmonary mucormycosis, 4 patients(6.8%) suffered from pulmonary candidiasis, 2 patients(3.4%) suffered from histoplasmosis, 1 patients(1.7%) suffered from actinomycetes pneumonia. Imaging manifestations of chest included lung mass in 23 cases(39.0%), exudative process in 23 cases(39.0%), lung nodes in 8 cases(13.6%), bronchus neoplasm in 3 cases(5.1%), cavitary lesions in 1 cases(1.7%), diffuse lesions in 1 cases(1.7%).Of the 59 patients, pulmonary fungal disease was misdiagnosed as pneumonia in 12 cases(20.3%), pulmonary tuberculosis in 7 cases(11.9%), and lung cancer in 4 cases(6.8%).Conclusion The pulmonary aspergillosis and cryptococcosis is common in pulmonary fungal disease diagnosed by pathology,and the imaging manifestations of chest mainly include lung mass and exudative process. Imaging manifestations of chest of pulmonary fungal disease are multifarious and have no characteristics. Thus diagnosis should be confirmed by pathological evidence as soon as possible.
Key words:  Pulmonary fungal disease  Pulmonary aspergillosis  Pulmonary cryptococcosis