| 摘要: |
| ［摘要］ 目的 探讨白细胞介素-6（IL-6）在急性胰腺炎合并急性肺损伤发生发展中的临床意义。方法 入选患者96例,分为急性胰腺炎组62例及急性胰腺炎合并急性肺损伤组34例，以健康成人30名为对照组。采用放射免疫法测定血清中IL-6含量变化，进行统计学分析。结果 急性胰腺炎组和急性胰腺炎合并急性肺损伤组IL-6值均高于对照组，急性胰腺炎合并急性肺损伤组高于急性胰腺炎组，差异均有统计学意义（P<0.05）。结论 IL-6作为炎症启动因子，参与急性胰腺炎合并肺损伤的病理生理过程。 |
| 关键词: 急性胰腺炎 急性肺损伤 白细胞介素-6 |
| DOI：10.3969/j.issn.1674-3806.2014.12.13 |
| 分类号:R 56;R 57 |
| 基金项目: |
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| Relationship between IL-6 and the acute pancreatitis with acute lung injury |
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WANG Jing, REN Li-mei, MENG Xian-mei, et al.
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Department of Digestive diseases，the Second Hospital Affiliated to Baotou Medical College, Inner Mongolia Autonomous Region,Neimenggu 014030, China
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| Abstract: |
| ［Abstract］ Objective To explore the clinical significance of IL-6 in the development of acute pancreatitis with acute lung injury.Methods Ninety-six acute pancreatitis patients were divided into acute panccreatitis group and acute panccreatitis with acute lung injury group randomly,and thirty healthy adults were selected as the control group. IL-6 was defected by radioimmunoassay and chemiluminescence, then the changes of IL-6 was analyzed statistically.Results The levels of IL-6 in acute panccreatitis group and acute panccreatitis with acute lung injury group were higher than that in the control group, the leves of IL-6 in acute pancreatitis with acut lung injury group was higher than that in acute pancreatitis group,all had statistical significance(P<0.05).Conclusion As an inflammation factor,IL-6 participates in the pathophy siological process of acute pancreatitis with acute lung injury. |
| Key words: Acute pancreatitis Acute lung injury IL-6 |
