| 摘要: |
| ［摘要］ 对比剂肾病（CIN）是一种血管造影术中使用对比剂出现的严重并发症，它在常见的医院获得性急性肾损伤中居第三位。对比剂肾病的发病机理尚不完全清楚，一些研究发现他汀类药物对预防对比剂肾病具有重要意义。虽然在一些患者中需要使用透析治疗，但CIN的治疗主要为支持治疗，包括小心液体的输入和电解质纠正，因此，最佳的治疗就是预防为主。该文主要对CIN的流行病学、发病机理和他汀类药物预防作用及可能机制进行综述。 |
| 关键词: 对比剂肾病 预防 他汀类药物 |
| DOI：10.3969/j.issn.1674-3806.2015.02.27 |
| 分类号:R 692 |
| 基金项目:广西卫生厅科研课题（编号：Z2013135） |
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| Progress in statins for preventing contrast-induced nephropathy |
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LUO Jun-chao, GONG Zhi-feng
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The First Department of Internal Medicine, Second Affiliated Hospital of Guangxi University of Science and Technology, Liuzhou 545006, China.
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| Abstract: |
| ［Abstract］ Contrast-induced nephropathy（CIN） is a serious complication after using angiography contrast material.It is the third common hospital-acquired acute kidney injury.The pathogenesis of CIN is still not entirely clear. Some studies have proved that statins are of great significant for preventing CIN. Although some patients need to use dialysis treatment, support treatment is still the main method for CIN, including careful inputting and correcting liquid electrolyte. Therefore, the best treatment is prevention. This paper mainly reviews the epidemiology and pathogenesis of CIN, and the effect and possible mechanism of statins in prevention of CIN. |
| Key words: Contrast-induced nephropathy Prevention Statins |
