| 摘要: |
| ［摘要］ 目的 探讨三维血流直方图定量分析在乳腺良恶性肿块内及周边血供评价中的应用价值。方法 根据手术病理结果将165例乳腺肿块患者分成恶性组93例，良性组72例。所有患者术前行三维超声检查，采用血流直方图定量分析肿块内及周边3 mm的体积（V）、血管指数（VI）、血流指数（FI）和血管血流指数（VFI），肿块内指标用V-in、VI-in、FI-in、VFI-in表示；肿块周边3 mm指标用V-out、VI-out、FI-out和VFI-out表示。将恶性组和良性组肿块的血流定量参数结果进行统计学比较。结果 乳腺肿块恶性组的VI-in、VFI-in、VI-out、FI-out及VFI-out测值均显著高于良性组（P<0.05），V-in、V-out及FI-in两组间测值均未见明显统计学差异（P>0.05）。ROC曲线分析显示，在有效的诊断指标中以VI-out诊断效能最高，VI-in、VFI-in、VFI-out次之，FI-out最差。结论 三维血流直方图定量分析能有效评估乳腺肿块内及周边血供情况。乳腺周边3 mm的血流定量参数在乳腺良恶性肿块的鉴别诊断中具有一定的应用价值。 |
| 关键词: 三维超声 直方图 乳腺肿块 |
| DOI：10.3969/j.issn.1674-3806.2015.04.03 |
| 分类号:R 445.1 |
| 基金项目:广西医疗卫生重点科研课题（编号：重200813）；广西科学研究与技术开发计划项目（编号：桂科攻0592007-2C） |
|
| Diagnosis value of quantitative analysis of vessels inside and adjacent to breast lesions using three-dimensional color histogram |
|
ZHANG Bing, WANG Xiao-yan, NONG Mei-fen, et al.
|
|
Departmen of Ultrasound, the People′s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China
|
| Abstract: |
| ［Abstract］ Objective To evaluate the distribution of vessels inside and adjacent to lesion region at three-dimensional color histogram can be used for the differentiation of benign and malignant breast lesions.Methods One hundred sixty five patients with breast lesions were divided into malignant lesion group(n=93) and benign lesion group(n=72), according to pathological findings. All cases underwent three-dimensional ultrasound exam. Three-dimensional color histogram was used to assess the volume and breast lesion indexes inside and outside 3 mm region, which included vascularization index(VI), flow index(FI）and vascularization-flow index(VFI ). Vascularity indexes inside were expressed respectively as V-in, VI-in, FI-in and VFI-in, and those outside surrounding region of 3 mm were expressed respectively as V-out, VI-out, FI-out and VFI-out. All the results were compared between malignant lesion group and benign lesion group.Results VI-in, VFI-in, VI-out, FI-out and VFI-out in malignant lesion group were significantly higher than those in benign lesion group(P<0.05). The indices of V-in, V-out and FI-in in the two groups had no significant differences(P>0.05). Based on the receiver operating characteristic(ROC) curve, VI-out was the best index for the diagnosis of breast lesions. VI-in, VFI-in and VFI-out were the second one, and FI-out was the last one.Conclusion The vascularity index of 3 mm surrounding region has certain value in the diagnosis of breast lesions. The quantitative analysis of three-dimensional color histogram has a certain value in assessing blood flow inside and adjacent to breast lesions and improves the differential diagnosis of benign and malignant breast lesions. |
| Key words: Three-dimensional ultrasonography Histogram Breast lesions |
