| 摘要: |
| ［摘要］ 目的 评估枸橼酸氢钾钠对肾结石患者经皮肾镜取石术后残留结石的清除和预防结石复发的效果。方法 选择154例因上尿路结石而行经皮肾镜取石术术后无结石残留或有结石残留的患者被纳入研究。根据结石清除情况将患者分为无残石组84例和有残石组70例，每组再随机分为治疗组和对照组。治疗组给予枸橼酸氢钾钠颗粒治疗，10 g/d，3次/d，疗程3个月；对照组不加用任何药物，饮食要求与治疗组相同，术后12个月比较治疗组和对照组结石复发率或结石生长情况。结果 无残石组接受药物治疗的患者12个月后结石复发率显著低于对照组（8.33% vs 38.46%，P<0.05），有残石组中接受药物治疗的患者结石增大的比率显著低于对照组（10.71% vs 59.37%，P<0.05）。结论 枸橼酸氢钾钠不仅显著降低经皮肾镜术后结石的复发率，而且抑制术后残留结石的生长。 |
| 关键词: 经皮肾镜取石术 枸橼酸氢钾钠 肾结石 |
| DOI：10.3969/j.issn.1674-3806.2015.11.06 |
| 分类号:R 692.4 |
| 基金项目:广西医疗卫生重点科研课题(编号：重2012104) |
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| Effect of potassium sodium hydrogen citrate therapy on stone recurrences and residual stones after percutaneous nephrolithotomy for renal calculi |
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LAN Zhi-xiang, WANG Wei, CAI Bin, et al.
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Department of Urology, the People′s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China
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| Abstract: |
| ［Abstract］ Objective To evaluate the efficacy of potassium sodium hydrogen citrate on residual stone removal and prevention of stone recurrence after percutaneous nephrolithotomy(PCNL) for renal calculi.Methods One hundred and fifty-four patients with residual stones or without residual stones after PCNL were enrolled in this study. Patients without residual stones(n=84) or with residual stones(n=70) were randomly divided into the treatment group and the control group respectively. The treatment group was given orally potassium sodium hydrogen citrate granules 10 g per day, and the control group was not treated with any medication. The stone recurrence was compared between the two groups after a follow-up of 12 months.Results For patients without residual stones, the stone recurrence rate in the treatment group was significantly lower than that in the control group(8.33% vs 38.46%, P<0.05). For patients with residual stones group, the stone growth rate in the treatment group was also significantly lower than that in the control group(10.71% vs 59.37%, P<0.05).Conclusion Potassium sodium hydrogen citrate therapy can not only reduce the stone recurrence, but also inhibit the residual stone growth after PCNL. |
| Key words: Percutaneous nephrolithotomy Potassium sodium hydrogen citrate Renal calculi |
