| 摘要: |
| ［摘要］ 目的 观察大剂量维生素C（VitC）联合地塞米松治疗鼻咽癌放疗后口咽溃疡的临床效果。方法 将鼻咽癌放疗后口咽溃疡患者62例按随机数字表法分为对照组（31例）和观察组（31例）。对照组采用常规治疗；观察组在对照组治疗的基础上加用维生素C 3 000 mg/d静脉推注+地塞米松10 mg溶于0.9%NaCl 250 ml静脉滴注，1次/d，7 d为一个疗程。结果 观察组与对照组总有效率分别为96.77%和61.29%，观察组疗效明显优于对照组（P<0.05）。结论 大剂量维生素C联合地塞米松治疗鼻咽癌放疗后口咽溃疡疗效显著。 |
| 关键词: 鼻咽癌放疗 口咽溃疡 大剂量维生素C 地塞米松 |
| DOI：10.3969/j.issn.1674-3806.2015.12.18 |
| 分类号:R 739.63 |
| 基金项目: |
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| Efficacy of high-dose vitamin C combination with dexamethasone in treatment of oropharyngeal ulcers after radiotherapy |
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JIANG Shou-zhe, WANG Tao, LIANG Yi-lei, et al.
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Department of Eye and ENT, the People′s Hospital of Wuming County, Nanning 530100, China
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| Abstract: |
| ［Abstract］ Objective To observe the clinical effects of high-doses of vitamin C combination with dexamethasone in the treatment of oropharyngeal ulcers after radiotherapy.Methods Oropharyngeal ulcer patients(n=62) of nasopharyngeal carcinoma after radiotherapy were randomly divided into the control group(n=31) and the treatment group(high-dose vitamin C+dexamethasone)(n=31). The control group was treated with conventional medication. The treatment group was treated with vitamin C 3 000 mg by intravenous injection(10 mg/d)+dexamethasone 10 mg in 0.9%Nacl 250 ml by intravenous drip on the basis of the same treatment in the control group, 1 time per day, 7 days for a period of treatment.Methods The effective rate was 96.77% and 61.29% in the treatment group and the control group respectively. There was significant difference in curative effect between the two groups(P<0.05).Conclusion Highdose of vitamin C combination with dexamethasone is effective in the treatment of oropharyngeal ulceration after radiotherapy. |
| Key words: Radiotherapy Oropharyngeal ulcers Highdose of vitamin C Dexamethasone |
