| 摘要: |
| ［摘要］ 目的 观察三子止咳胶囊联合噻托溴铵治疗稳定期慢性阻塞性肺疾病（COPD）的临床疗效。方法 将56例COPD患者随机分为两组各28例，对照组应用噻托溴铵，实验组在对照组基础上加用三子止咳胶囊。观察两组治疗前后肺功能、呼吸困难指数及急性加重次数。结果 (1)两组患者入组时性别、年龄、肺功能、呼吸困难指数及过去1年急性加重次数差异无统计学意义。(2)治疗1年后评估，实验组肺功能下降较对照组缓慢，呼吸困难指数、急性加重次数减少（P<0.05）。结论 三子止咳胶囊联合噻托溴铵可延缓肺功能下降的速度，改善呼吸困难指数，减少急性加重次数。 |
| 关键词: 三子止咳胶囊 噻托溴铵 慢性阻塞性肺疾病 |
| DOI：10.3969/j.issn.1674-3806.2016.01.07 |
| 分类号:R 563 |
| 基金项目: |
|
| The effects of Sanzizhike capsule and tiotropium in the treatment of COPD in stable stage |
|
ZHANG Zhi-yang, CAI Wei-ping, LIN Zhi-ping, et al.
|
|
Department of Cardiology, the Hospital of Anxi County, Fujian 362400, China
|
| Abstract: |
| ［Abstract］ Objective To observe the effects of Sanzizhike capsule and tiotropium in the treatment of chronic obstructive plumonary disease(COPD) in stable stage.Methods Fifty-six patients with COPD in stable stage were randomly divided into two groups.The experimental group received Sanzizhike capsule with tiotropium while the control group was treated with tiotropium. Lung function, mMRC(modified medical research council) and the number of acute exacerbations were observed before and after the treatment in the two groups.Results (1)There were no significant differences between the experimental group and the control group in gender, age, mMRC, lung function and the number of acute exacerbations. (2)One year after the treatment, mMRC, spirometry and the number of acute exacerbation in experimental group decreased significantly compared with those before the treatment, but these decreases were significantly slower than those in the control group(P<0.05).Conclusion Sanzizhike capsule and tiotropium can reduce the rate of decline in lung function and the number of acute exacerbation, and also improve the mMRC. |
| Key words: Sanzizhike capsule Tiotropium Chronic obstructive pulmonary disease(COPD) |
