| 摘要: |
| ［摘要］ 目的 分析新生儿呼吸机相关性肺炎（ventilator-associated pneumonia,VAP）的影响因素和发病情况，寻求预防新生儿VAP发生的措施。方法 对133例使用呼吸机治疗48 h以上患儿的临床资料进行回顾分析，以58例VAP患儿为研究组，75例未患VAP患儿为对照组。分析新生儿VAP的发病率及与出生体重、胎龄、插管次数、机械辅助通气时间的关系，引起VAP的病原菌。结果 在使用呼吸机治疗48 h以上的新生儿中VAP发病率为43.6%；革兰阴性杆菌为主要病原菌；胎龄越小，出生体重越低，插管次数越多及机械辅助通气时间越长的患儿，VAP发病率越高。结论 减少机械辅助通气时间，避免多次插管，根据细菌培养及药敏结果选用抗菌药物，对原发病进行积极处理，可以降低新生儿VAP发病率。 |
| 关键词: 新生儿 呼吸机相关性肺炎 临床分析 |
| DOI：10.3969/j.issn.1674-3806.2016.04.16 |
| 分类号:R 725.6 |
| 基金项目: |
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| Clinical research of neonatal ventilator-associated pneumonia in 58 cases |
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ZHAO Quan-en, LIAO Pei-chan, HUANG Ge-ping
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Department of Pediatrics, the Second People′s Hospital of Xinhui District of Jangmen City, Guangdong 529100, China
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| Abstract: |
| ［Abstract］ Objective To study the influent factors and incidence of neonatal ventilator-associated pneumonia(VAP) and the measures of preventing neonatal VAP.Methods A retrospective analysis of 133 neonates with ventilator treatment more than 48 hours was conducted. The incidence of VAP was studied in 58 cases with VAP(the study group) and in 75 cases without VAP(the control group). The relationships between the incidence of VAP and birth weight, gestational age, times of cannula and time of mechanic ventilation were studied. The pathogenic bacteria of VAP were isolated.Results The incidence of VAP was 43.6% in the neonates with ventilator treatment more than 48 hours. Gram-Negative bacilli were the main pathogenic bacteria. The higher incidence of neonatal VAP, the younger gestational age, the lower birth weight, the more times of tracheal cannula and the longer time of mechanic ventilation the neonates got.Conclusion Shortening the time of mechanic ventilation, reducing the times of tracheal cannula and using antibacterials according to germiculture and drug sensitivity resuits, may reduce the incidence of neonatal VAP. |
| Key words: Neonate Ventilator-associated pneumonia(VAP) Clinicail research |
