引用本文:孔令常,张龙洲.内镜辅助下经鼻蝶入路手术治疗垂体瘤的临床效果观察[J].中国临床新医学,2018,11(12):1233-1236.
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内镜辅助下经鼻蝶入路手术治疗垂体瘤的临床效果观察
孔令常,张龙洲
450000 河南,郑州市中医院神经外科(孔令常);450052 河南,郑州大学第一附属医院神经外科(张龙洲)
摘要:
[摘要] 目的 探讨内镜辅助下经鼻蝶入路手术治疗垂体瘤的临床效果。方法 将该院2017-05~2018-05收治的92例垂体瘤患者,根据手术方法不同分为对照组和研究组,对照组行经鼻蝶显微镜垂体瘤切除术治疗,研究组行内镜辅助下经鼻蝶入路手术治疗。对比两组患者的临床疗效及两组患者内分泌激素水平及术后并发症发生情况。结果 研究组的临床疗效优于对照组(P<0.01),同时研究组的术后并发症总发生率显著低于对照组(P<0.01);治疗后研究组血管紧张素、肾素、去甲肾上腺素等内分泌激素水平低于对照组(P<0.01)。结论 内镜辅助下经鼻蝶入路手术治疗垂体瘤患者的效果更佳,患者内分泌激素水平的影响相对较低,治疗有效率高,不良反应少,值得进一步推广。
关键词:  内镜辅助  经鼻蝶入路手术  垂体瘤  疗效  内分泌激素
DOI:10.3969/j.issn.1674-3806.2018.12.16
分类号:R 736.4
基金项目:
Clinical effect of endoscope-assisted transsphenoidal approach on treatment of pituitary adenomas
KONG Ling-chang, ZHANG Long-zhou
Department of Neurosurgery, Zhengzhou Hospital of Traditional Chinese Medicine, Henan 450000, China
Abstract:
[Abstract] Objective To investigate the clinical effect of endoscope-assisted transsphenoidal approach on treatment of pituitary adenomas. Methods 92 patients with pituitary adenomas treated in our hospital from May 2017 to May 2018 were randomly divided into control group and study group. The control group was treated with pituitary adenoma resection via microscope nasal transsphenoidal resection, and the study group received pituitary adenoma resection by endoscope-assisted transsphenoidal approach. The clinical effects, the endocrine hormone levels and the postoperative complications were compared between the two groups. Results The clinical effect of the study group was better than that of the control group(P<0.01), and the incidence postoperative complications in the study group was significantly lower than that in the control group(P<0.01). The levels of angiotensin, renin, norepinephrine and other endocrine hormones in the study group were better than those in the control group after treatment(P<0.01). Conclusion Endoscope-assisted transsphenoidal approach is more effective in the treatment of pituitary adenomas and the impacts of endocrine hormone levels is relatively less.
Key words:  Endoscope-assisted  Transsphenoidal approach  Pituitary adenomas  Clinical effect  Endocrine hormones