引用本文:周 新.侵袭性肺曲霉病诊治需要注意的几个问题[J].中国临床新医学,2019,12(1):1-4.
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侵袭性肺曲霉病诊治需要注意的几个问题
周 新
200080 上海,上海交通大学附属第一人民医院呼吸与危重症医学科
摘要:
[摘要] 近20年来侵袭性肺曲霉病(invasive pulmonary aspergillosis,IPA)作为器官移植受者、骨髓干细胞移植受者以及合并有慢性肺部疾病患者主要的并发症在临床上明显增多,也是患者致残和死亡的原因之一。该文就IPA诊治过程中需要注意的几个问题,如IPA的诊断标准、肺曲霉病的分类、半乳甘露聚糖抗原(galactomannan,GM)试验和1,3-β-D葡聚糖(G试验)检测对IPA诊断的价值、IPA的临床处理原则以及IPA的抗真菌药物治疗等问题作一讨论。
关键词:  侵袭性肺曲霉病  诊断  治疗  抗真菌药物
DOI:10.3969/j.issn.1674-3806.2019.01.01
分类号:R 519.1
基金项目:
Noticeable problems in diagnosis and treatment of invasive pulmonary aspergillosis
ZHOU Xin
Department of Respiratory and Critical Care Medicine, the First People′s Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200080, China
Abstract:
[Abstract] Invasive pulmonary aspergillosis(IPA) represents a major complication in recipients of hematopoietic stem cell transplantation and solid-organ transplantation.The incidence of IPA in transplant recipients and in patients who have underlying lung diseases has increased over the past 20 years, and these infections continue to be associated with high morbidity and mortality. This article reviews some problems in terms of IPA diagnosis standard, classification of pulmonary aspergillosis, GM test and G test diagnostic value and clinical management of IPA.
Key words:  Invasive pulmonary aspergillosis(IPA)  Dignosis  Treatment  Antifungal drugs