摘要: |
[摘要] 镍纹样蛋白(Metrnl)作为一种新的脂肪因子,在人体内广泛分布。心肌缺血后的血运重建引起的心肌缺血再灌注损伤(MIRI)严重影响急性心肌梗死(AMI)患者的治疗预后,而Metrnl与MIRI的改善有着密切关系。该文就Metrnl与MIRI关系的研究进展作一综述。 |
关键词: 镍纹样蛋白 心肌缺血再灌注损伤 内质网应激 |
DOI:10.3969/j.issn.1674-3806.2021.07.20 |
分类号:R 541 |
基金项目:国家自然科学基金项目(编号:81860797) |
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Research progress of Metrnl and myocardial ischemia-reperfusion injury |
MI Yong-cheng, HUANG Zhao-he
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Graduate School of Youjiang Medical University for Nationalities, Guangxi 533000, China
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Abstract: |
[Abstract] Meteorin-like protein(Metrnl), as a new adipokine, is widely distributed in human body. Myocardial ischemia-reperfusion injury(MIRI) caused by revascularization after myocardial ischemia seriously affects the prognosis of patients with acute myocardial infarction(AMI), and Metrnl is closely related to the improvement of MIRI. This paper reviews the research progress of the relationship between Metrnl and MIRI. |
Key words: Meteorin-like protein(Metrnl) Myocardial ischemia-reperfusion injury(MIRI) Endoplasmic reticulum stress(ERS) |