| 摘要: |
| ［摘要］ 原发性肝癌是最常见的恶性肿瘤之一，肝癌早期诊断困难，总体手术切除率低，传统非手术治疗效果欠佳。肝癌的转化治疗是通过局部/系统治疗将不可切除肝癌转为可切除肝癌，并从手术切除获益。近年来，免疫检查点抑制剂治疗在晚期肝癌的治疗中取得较大突破，以肝动脉灌注化疗为代表的局部治疗的进步，使部分中晚期肝癌患者重新获得手术机会并因此获益。该文对肝细胞癌转化治疗的研究进展进行综述。 |
| 关键词: 肝细胞癌 转化治疗 肝切除术 |
| DOI：10.3969/j.issn.1674-3806.2022.05.20 |
| 分类号:R 735.7 |
| 基金项目: |
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| Research progress in conversion therapy of hepatocellular carcinoma |
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QIN Jian-lun, QIN Wei, MO Shu-tian, et al.
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Department of General Surgery, the Third People′s Hospital of Hechi City, Guangxi 547000, China
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| Abstract: |
| ［Abstract］ Primary liver cancer is one of the most common malignancies. The early diagnosis of liver cancer is difficult. The overall surgical resection rate of liver cancer is low and the effect of traditional non-surgical treatment is not good. The conversion therapy of liver cancer is to convert unresectable liver cancer into resectable liver cancer through local/systemic treatment and benefit from surgical resection. In recent years, checkpoint inhibitor therapy has made a greater breakthrough in the treatment of advanced liver cancer. Some patients with moderate and advanced liver cancer have regained the opportunity of operation and benefited from the progress of local treatment represented by hepatic artery infusion chemotherapy(HAIC). This paper reviews the research progress in conversion therapy of hepatocellular carcinoma. |
| Key words: Hepatocellular carcinoma(HCC) Conversion therapy Hepatectomy |
