| 摘要: |
| ［摘要］ 银屑病是一种由免疫因素介导的常见慢性、复发性、炎症性疾病。目前，其病因及发病机制尚未明确。随着科学技术的进步，研究发现微小RNA（miRNA）在免疫系统的发育和调节及银屑病发病机制中均起重要作用。该文对参与银屑病发病机制的miRNA的各种研究结果及miRNA对银屑病的治疗作用的研究进展进行综述。 |
| 关键词: 微小RNA 银屑病 发病机制 治疗 |
| DOI：10.3969/j.issn.1674-3806.2022.11.20 |
| 分类号:R 759 |
| 基金项目:国家自然科学基金项目（编号：81160194）；广西自然科学基金项目（编号：2013GXNSFAA019227） |
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| Research progress of miRNA in pathogenesis and treatment of psoriasis |
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XIE Zhi, LI li-li
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Department of Dermatology, the People′s Hospital of Guangxi Zhuang Autonomous Region(Guangxi Academy of Medical Sciences), Nanning 530021, China
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| Abstract: |
| ［Abstract］ Psoriasis is a common, chronic, recurrent, inflammatory disease mediated by immune factors. At present, the etiology and pathogenesis of psoriasis are not clear. With the advancement of science and technology, studies have found that micro ribonucleic acid(microRNA, miRNA) plays an important role in the development and regulation of the immune system and the pathogenesis of psoriasis. This paper reviews the research results of miRNA involved in the pathogenesis of psoriasis and the research progress of the therapeutic effects of miRNA on psoriasis. |
| Key words: Micro ribonucleic acid(miRNA) Psoriasis Pathogenesis Treatment |
