引用本文:程东良，史长松.体外膜肺氧合在儿童脓毒症休克中的临床应用[J].中国临床新医学,2023,16(7):673-677.
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体外膜肺氧合在儿童脓毒症休克中的临床应用
程东良，史长松
450003　郑州，河南省人民医院（郑州大学人民医院）儿童重症监护室
摘要:
［摘要］　脓毒症休克目前仍是全球范围内导致儿童死亡的重要原因，脓毒症休克可导致低血压和低灌注，导致氧输送（DO2）减少，从而出现氧供/氧耗失衡。体外膜肺氧合（ECMO）可以增加DO2，增加氧供，所以ECMO有救治脓毒症休克的理论基础。ECMO救治脓毒症休克的疗效欠佳，主要与ECMO启动时机、ECMO中心的经验、是否为中央插管和ECMO高流量等相关。该文对ECMO在儿童脓毒症休克中的临床应用进行综述。
关键词:  体外膜肺氧合  儿童  脓毒症休克
DOI：10.3969/j.issn.1674-3806.2023.07.07
分类号:R 720.597
基金项目:
Clinical application of extracorporeal membrane oxygenation in septic shock in children
CHENG Dong-liang, SHI Chang-song
Pediatric Intensive Care Unit, Henan Provincial People′s Hospital(People′s Hospital of Zhengzhou University), Zhengzhou 450003, China
Abstract:
［Abstract］　Septic shock is still an important cause of death in children worldwide. Septic shock can lead to hypotension and hypoperfusion, resulting in reduced oxygen delivery(DO2) and oxygen supply/oxygen consumption imbalance. Extracorporeal membrane oxygenation(ECMO) can increase DO2 and oxygen supply, so ECMO has a theoretical basis for treating septic shock. The unsatisfactory therapeutic efficacy of ECMO in the treatment of septic shock is mainly related to the timing of ECMO initiation, the experience of ECMO centers, whether it is central venous intubation and high flow rate of ECMO. This paper reviews the clinical application of extracorporeal membrane oxygenation in septic shock in children.
Key words:  Extracorporeal membrane oxygenation(ECMO)  Children  Septic shock