引用本文:耿丽群,寇民生,耿爱群.急性心肌梗死患者血清钾浓度与CK-MB的相关性分析及其对预后的影响[J].中国临床新医学,2019,12(8):899-901.
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急性心肌梗死患者血清钾浓度与CK-MB的相关性分析及其对预后的影响
耿丽群,寇民生,耿爱群
462000 河南,漯河医学高等专科学校第三附属医院心内科(耿丽群,寇民生);462000 河南,漯河医学高等专科学校第二附属医院超声科(耿爱群)
摘要:
[摘要] 目的 分析急性心肌梗死患者血清钾离子水平与血清肌酸磷酸激酶同工酶(CK-MB)的相关性,探讨血清钾升高对心肌梗死急性期预后的影响。方法 96例急性心肌梗死患者于发病16 h静脉采血检测血钾和CK-MB浓度,根据血钾水平将患者分为正常血钾组36例、轻度升高组33例及明显升高组27例,分析比较三组患者在急性期心律失常、休克、心力衰竭及死亡发生率。结果 血钾浓度与CK-MB呈正相关关系,相关系数为0.920。血钾明显升高组心律失常、心力衰竭、休克以及死亡发生率分别为63.0%、59.3%、51.9%、66.7%,显著高于正常血钾组(27.8%、8.3%、2.8%、2.8%)和轻度升高组(57.6%、24.2%、18.2%、21.2%),差异有统计学意义(P<0.01)。结论 急性心肌梗死患者血钾浓度升高是出现严重并发症及死亡的重要危险因素,是预后不良的重要指标。
关键词:  心肌梗死  血清钾  肌酸磷酸激酶同工酶  预后
DOI:10.3969/j.issn.1674-3806.2019.08.20
分类号:R 542.2+2
基金项目:
Correlation between serum potassium concentration and CK-MB in patients with acute myocardial infarction and the effect of serum potassium concentration on the patients′ prognosis
GENG Li-qun, KOU Min-sheng, GENG Ai-qun
Department of Cardiology, the Third Affiliated Hospital of Luohe Medical College, Henan 462000, China
Abstract:
[Abstract] Objective To study the correlation between the level of serum potassium and creatine kinase-MB(CK-MB) in patients with acute myocardial infarction, and to investigate the effect of elevated serum potassium on the prognosis of acute myocardial infarction. Methods The venous blood were collected and the blood potassium and CK-MB concentration were detected in 96 acute myocardial infarction patients at 16 hours of onset. The patients were divided into three groups according to different blood potassium levels: normal blood potassium group(n=36), slightly increased group(n=33), significantly increased group(n=27). The incidence rates of arrhythmia, shock, heart failure and death were compared among the three groups. Results The blood potassium concentration was positively correlated with CK-MB, and the correlation coefficient was 0.920. The incidence rates of arrhythmia, heart failure, shock and death was 63.0%, 59.3%, 51.9% and 66.7% in the significantly increased group, and 27.8%, 8.3%, 2.8% and 2.8% in the normal blood potassium group, and 57.6%, 24.2%, 18.2% and 21.2% in the slightly increased group. The rates of the significantly increased group were significantly higher than those in the normal blood potassium group and the slightly increased group(P<0.01). Conclusion The increase of serum potassium concentration in patients with acute myocardial infarction is an important independent risk factor for serious complications and death and is an important indicator of poor prognosis in acute myocardial infarction.
Key words:  Myocardial infarction  Serum potassium  Creatine kinase-MB(CK-MB)  Prognosis