| 摘要: |
| ［摘要］ 目的 探讨应用脑干听觉诱发电位(BAEP)诊断新生儿高胆红素血症的临床价值。方法 选择2017-08～2019-08阳春市妇幼保健院收治的98例高胆红素血症新生儿作为观察组，另选择同期98名健康新生儿作为对照组。两组均施行BAEP检测，并比较检测结果。结果 观察组有71例（72.45%）发生BAEP异常，对照组有6例（6.12%）发生BAEP异常，两组BAEP异常率比较差异有统计学意义（χ2=90.374，P=0.000）。观察组各时期BAEP水平及反应阈值均显著高于对照组（P<0.05）。血清胆红素重度异常者的BAEP异常率显著高于中度异常者和轻度异常者（P<0.05），中度异常者的BAEP异常率亦显著高于轻度异常者（P<0.05）。结论 应用BAEP诊断新生儿高胆红素血症具有较好的临床价值，有助于尽早了解患儿听力及脑干功能损害情况，从而便于尽早开展对症治疗。 |
| 关键词: 脑干听觉诱发电位 新生儿 高胆红素血症 诊断 |
| DOI：10.3969/j.issn.1674-3806.2021.02.11 |
| 分类号:R 722.17 |
| 基金项目:阳江市科学技术局科研项目（编号：SF2020195） |
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| Clinical application value of brainstem auditory evoked potentials in diagnosis of neonatal hyperbilirubinemia |
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LIN Fei-hong, LAN Shui-nong, CHEN Li-ming, et al.
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Department of Neonatology, Yangchun Maternal and Child Health Hospital, Guangdong 529600, China
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| Abstract: |
| ［Abstract］ Objective To explore the clinical value of brainstem auditory evoked potentials(BAEP) in diagnosis of neonatal hyperbilirubinemia. Methods From August 2017 to August 2019, ninety-eight newborns with hyperbilirubinemia admitted to Yangchun Maternal and Child Health Hospital were selected as the observation group, and 98 healthy newborns during the same period were selected as the control group. The detection of BAEP was performed in both groups and the results were compared. Results There were 71 cases(72.45%) with abnormal BAEP in the observation group and 6 cases(6.12%) in the control group. There was significant difference in the BAEP abnormal rate between the two groups(χ2=90.374, P=0.000). The BAEP level and response threshold of the observation group were significantly higher than those of the control group in each period(P<0.05). The abnormal rate of BAEP in patients with severely abnormal serum bilirubin was significantly higher than that in patients with moderately and mildly abnormal serum bilirubin(P<0.05), and the abnormal rate of BAEP in patients with moderately abnormal serum bilirubin was also significantly higher than that in patients with mildly abnormal serum bilirubin(P<0.05). Conclusion Application of BAEP has better clinical value in diagnosis of neonatal hyperbilirubinemia, which is conducive to the early understanding of the hearing and brainstem function impairment of the pediatric patients with neonatal hyperbilirubinemia, so as to perform the symptomatic treatment as early as possible. |
| Key words: Brainstem auditory evoked potentials(BAEP) Newborns Hyperbilirubinemia Diagnosis |
