引用本文:袁雪娇，张若鹏.肠道菌群及其代谢产物对复发性流产影响的研究进展[J].中国临床新医学,2024,17(2):222-226.
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肠道菌群及其代谢产物对复发性流产影响的研究进展
袁雪娇，张若鹏
昆明市妇幼保健院（大理大学昆明市妇幼保健院研究生培养基地），云南 671000
摘要:
［摘要］　复发性流产（RSA）在育龄期女性中发病率约为5%，严重影响女性身心健康。健康成年人肠道菌群的种类和数量处于动态平衡，肠道菌群紊乱会影响多种生殖内分泌疾病发生、发展，妊娠期母体肠道菌群组成发生显著改变。该文就肠道菌群及其代谢产物对RSA影响的研究进展作一综述。
关键词:  肠道菌群  复发性流产  益生菌  氧化三甲胺
DOI：10.3969/j.issn.1674-3806.2024.02.19
分类号:R 711
基金项目:国家自然科学基金项目（编号：82260309）
Research progress in the effects of intestinal floras and their metabolites on recurrent spontaneous abortion
YUAN Xuejiao, ZHANG Ruopeng
Kunming City Maternal and Child Health Hospital(Postgraduate Training Base of Kunming City Maternal and Child Health Hospital of Dali University), Yunnan 671000, China
Abstract:
［Abstract］　The incidence rate of recurrent spontaneous abortion(RSA) in women of childbearing age is about 5%, which seriously affects women′s physical and mental health. The types and quantity of intestinal floras in healthy adults are in a dynamic balance. The disturbance of intestinal floras may affect the occurrence and development of various reproductive endocrine diseases. The composition of maternal intestinal floras during pregnancy undergoes significant changes. This paper reviews the research progress in the effects of intestinal floras and their metabolites on RSA.
Key words:  Intestinal flora  Recurrent spontaneous abortion(RSA)  Probiotics  Trimethylamine
N-oxide(TMAO)