| 引用本文: | 张洁,曹晓玮,张欣.济南地区膳食摄入与代谢综合征各要素对高尿酸血症的影响[J].中国临床新医学,0,():-. |
| ZHANG Jie,CAO Xiao-wei,ZHANG Xin.济南地区膳食摄入与代谢综合征各要素对高尿酸血症的影响[J].中国临床新医学,0,():-. |
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| 摘要: |
| 目的 探讨济南地区膳食摄入与代谢综合征各要素对高尿酸血症(hyperuricemia,HUA)的影响,为HUA的预防控制提供科学指导。方法 采用简单随机方法选取山东省立医院健康管理中心查体的济南市常住居民中符合高尿酸血症标准者和正常者各100例作为病例组和对照组进行病例对照研究,并收集被调查者基本信息、生活饮食习惯、身体测量和生化指标等资料。结果 多元线性回归分析显示体质指数、总胆固醇、甘油三酯、低密度脂蛋白、肌酐水平影响血尿酸水平,有正相关关系,高密度脂蛋白影响血尿酸水平,有负相关关系。二分类Logistic回归分析显示：吸烟史、啤酒、补充维生素C、动物内脏、甜饮料、粗粮与血尿酸水平存在相关性。结论 体质指数超标、高血脂均与高尿酸血症有关联。减少饮酒,少食动物内脏类等富含嘌呤的食物,补充维生素C,多吃粗粮可以预防或者减少高尿酸血症的发生。 |
| 关键词: 高尿酸血症 膳食 代谢综合征 病例对照研究 |
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| 基金项目:山东省科技发展计划重点研发计划项目(课题号：2018GSF118063), 山东省医药卫生科技发展计划(课题号：2016WS0417)。 |
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| Effects of dietary intake and metabolic syndrome on hyperuricemia in Jinan |
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ZHANG Jie,CAO Xiao-wei,ZHANG Xin
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Department of Nutrition,Shandong Provincial Hospital affiliated to Shandong University
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| Abstract: |
| Objective To investigate the effects of dietary intake and metabolic syndrome on hyperuricemia (HUA) in Jinan city and provide scientific guidance for the prevention and control of HUA. Methods 100 patients who were eligible for hyperuricemia and 100 cases of normal medical examination from the permanent residents of Jinan city examined in the Health Management Center of Shandong Provincial Hospital were randomly selected using a simple method as a case group and a control group for case-control study. Basic information, dietary habits, body measurements and biochemical indicators were collected. Results Multiple linear regression analysis showed that body mass index, total cholesterol, triglyceride, low density lipoprotein and creatinine levels affected blood uric acid level and there was a positive correlation. High density lipoprotein affected blood uric acid level and there was a negative correlation. Two-category logistic regression analysis showed that there is a correlation of smoking history, beer, vitamin C supplementation, animal internal organs, sweet drinks, coarse grains with blood uric acid levels. Conclusion Excessive body mass index, hypertension and hyperlipidemia are associated with hyperuricemia. Reducing alcohol consumption, eating less animal organs and other foods rich in purine, adding vitamin C, eating more coarse grains can prevent or reduce the occurrence of hyperuricemia. |
| Key words: Hyperuricemia Diet Metabolic syndrome Case-control study |
