| 引用本文: | 王清秀,韩校鹏,王赛男,曹婷.CURB-age评分联合炎症因子对老年社区获得性肺炎预后的评估价值[J].中国临床新医学,0,():-. |
| wangqingxiu,han xiaopeng,wang sainan,cao ting.CURB-age评分联合炎症因子对老年社区获得性肺炎预后的评估价值[J].中国临床新医学,0,():-. |
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| 摘要: |
| [摘要] 目的 探讨CURB-age评分联合炎症因子对老年CAP患者短期预后的评估价值。方法 收集郑州大学第二附属医院2016年1月至2020年2月住院治疗的老年CAP患者112例。收集并分析患者的临床及实验室资料，比较存活组和死亡组各指标间的差异，采用多因素Logistic 回归分析确定影响老年CAP患者预后的独立危险因素，绘制ROC曲线，分析联合模型对老年CAP患者30天内死亡的预测价值。结果 死亡组患者的CURB-age评分、CURB-65评分、C反应蛋白（CRP）、C反应蛋白和前白蛋白比值（CRP/PA） 、降钙素原（PCT）、白细胞计数（WBC）均高于存活组（P＜0.05）,死亡组患者的前白蛋白（PA）低于存活组（P＜0.05）。多因素Logistic回归分析显示CURB-age评分是老年CAP患者30天内死亡的独立危险因素，OR值为5.529[95%CI（1.401,21.819）]，P＜0.05。联合模型的ROC曲线分析发现PA能够提高CURB-age评分对老年CAP患者死亡结局的预测效能。CURB-age评分+PA组合模型预测患者死亡结局的AUC为0.947[95%CI(0.905,0.990)]，P＜0.05。结论 CURB-age评分对老年CAP患者的短期预后具有良好的临床预测价值，且优于CURB-65评分，联合PA将显著提高其预后预测价值。 |
| 关键词: 社区获得性肺炎 老年 炎症因子 预后 CURB-age评分 |
| DOI： |
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| 基金项目:河南省基础与前沿技术研究计划项目 |
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| The value of CURB-age score combined with inflammatory factors in evaluating the prognosis of elderly community-acquired pneumonia |
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wangqingxiu, han xiaopeng, wang sainan, cao ting
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the Second Affiliated Hospital of Zhengzhou University
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| Abstract: |
| [Abstract] Objective To explore the evaluation value of CURB-age score combined with inflammatory factors in short-term prognosis of elderly CAP patients. Methods A total of 112 elderly patients with CAP hospitalized in the second affiliated Hospital of Zhengzhou University from January 2016 to February 2020 were collected.The clinical and laboratory data were collected and analyzed,To compare the differences between the indicators in the survival group and the death group, the independent risk factors influencing the prognosis of elderly patients with CAP were determined by multivariate Logistic regression analysis. and the ROC curve was drawn to analyze the predictive value of the combined models for the death of elderly CAP patients within 30 days.Results The CURB-age score, CURB-65 score, C-reactive protein (CRP), C-reactive protein to prealbumin ratio (CRP/PA), procalcitonin (PCT), and white blood cell count (WBC) of the death group were higher than those of the survival group (P<0.05), the prealbumin (PA) of the death group was lower than that of the survival group (P<0.05). Multivariate Logistic regression analysis showed that the CURB-age score was an independent risk factor for death within 30 days in elderly patients with CAP with an OR value of 5.529[95%CI (1.401,21.819)], P < 0.05.The ROC curve analysis of the combined models found that PA can improve the predictive value of the CURB-age score for the death outcome of elderly CAP patients. The AUC of the CURB-age score+PA combined model predicting the death outcome of the patients was 0.947[95%CI(0.905,0.990)], P＜0.05.Conclusion The CURB-age score has a good clinical predictive value for the short-term prognosis of elderly CAP patients, and is better than the CURB-65 score. PA may significantly improve the prognostic value of CURB-age score. e in predicting death. |
| Key words: Community-acquired pneumonia inflammatory factors elderly Prognosis CURB-age score |
