| 摘要: |
| 目的 探讨下肢深静脉血栓（DVT）患者血栓弹力图（TEG）与常规凝血试验的相关性与一致性。方法 回顾性分析2017-09～2021-01安徽医科大学附属合肥医院介入科收治的87例DVT住院患者。收集患者血栓弹力图实验与常规凝血试验等临床资料，对二者结果进行统计学分析。结果 血栓弹力图中相关参数与常规凝血试验指标具有明显相关性，TEG的R值与PT、APTT呈正相关（r=0.231，r=0.395）；TEG的K值与APTT呈正相关（r=0.237），与FIB、PLT呈负相关（r=-0.521、-0.431）；TEG的α-Angle与FIB、PLT值呈正相关（r=0.542、0.471）；TEG的MA值与FIB、PLT值呈正相关（r=0.674、0.596），差异均有统计学意义（P＜0.05）。TEG的MA 值与PLT、FIB的Kappa值分别是0.148、0.210，差异均有统计学意义（P＜0.05）。结论 对于DVT患者，其血栓弹力图实验与常规凝血试验呈现显著相关性，但二者一致性较差，两种方法尚无法相互替代。TEG提供了常规凝血试验之外的补充信息，值得在临床进一步应用推广。 |
| 关键词: 下肢深静脉血栓 凝血功能检测 血栓弹力图 常规凝血试验 |
| DOI： |
| 分类号: |
| 基金项目: |
|
| Correlation and Consistency of Two Different Methods for Detecting Coagulation Function in Patients with Lower Extremity Deep Venous Thrombosis |
|
ZHANG Haodang, PAN Shengquan
|
|
Department of Intervention,Hefei hospital affiliated to Anhui Medical University,Hefei
|
| Abstract: |
| Objective To investigate the correlation and consistency between Thrombelastography (TEG) and routine coagulation test in patients with deep venous thrombosis (DVT). Methods 87 inpatients with DVT of the interventional Department of Hefei hospital affiliated to Anhui Medical University from September 2017 to January 2021 were retrospectively reviewed. The clinical data of thromboelastography and routine coagulation test were collected, and the detection results of 2 different methods were statistically analyzed. Results There was correlation between the TEG and routine coagulation test with all P＜0.05. R time was positively correlated with PT and APTT ( r = 0.231, 0.395) .K was positively correlated with APTT ( r = 0.237) ,but negatively correlated with FIB and PLT (r=-0.521, -0.43). α-angle was positively correlated with FIB and PLT (r=0.542, 0.471). Moreover, MA were positively correlated with FIB and PLT (r = 0.674, 0.596). The Kappa values of MA in thrombelastometry with PLT, FIB were respectively 0.148, 0.210 (both P＜0.05). Discussion For DVT patients, TEG and routine coagulation test showed significant correlation, but the consistency between them was poor, so the 2 kinds of methods can not be replaced for each other. TEG provides additional information besides routine coagulation test, which is worth further clinical application. |
| Key words: venous thrombosis coagulation function detection thromboelastography routine coagulation test |
