引用本文:柴夏宁,王新文,杨敏,赵继敏,王杰,丁金祥,高楠琳.AF患者术前CT左心耳成像测定LAA开口参数与LAAO术中置入封堵器尺寸的关联性以及术后PDL发生的影响因素分析[J].中国临床新医学,0,():-.
.AF患者术前CT左心耳成像测定LAA开口参数与LAAO术中置入封堵器尺寸的关联性以及术后PDL发生的影响因素分析[J].中国临床新医学,0,():-.
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AF患者术前CT左心耳成像测定LAA开口参数与LAAO术中置入封堵器尺寸的关联性以及术后PDL发生的影响因素分析
柴夏宁1, 王新文2, 杨敏1, 赵继敏1, 王杰1, 丁金祥1, 高楠琳1
1.山西医科大学;2.山西医科大学第二医院
摘要:
[摘要] 目的 分析房颤(AF)患者术前电子计算机断层扫描(CT)左心耳成像测定左心耳(LAA)开口参数与左心耳封堵术(LAAO)中置入封堵器尺寸的相关性以及术后器械周围残余分流(PDL)发生的影响因素。方法 回顾性分析2019年1月至2022年12月于山西医科大学第二医院成功实施LAAO的83例非瓣膜性AF患者临床资料。根据术后发生PDL情况将其分为PDL组(23例)和无PDL组(60例)。比较两组患者的临床资料和LAA开口参数。采用Pearson相关分析LAA开口参数与LAAO术中置入封堵器尺寸的关联性。采用logistic回归分析LAAO术后发生PDL的危险因素。 结果 PDL组患者年龄显著小于无PDL组(P<0.05),两组患者性别、合并基础疾病情况比较差异无统计学意义(P>0.05)。PDL组LAA开口长径、短径、周长、面积均大于无PDL组,差异有统计学意义(P<0.05)。Pearson相关分析结果显示,无PDL组LAA开口的长径、短径、周长、面积与置入封堵器尺寸均呈正相关(P<0.05)。多因素logistic回归分析结果显示,较小的年龄、较大的LAA开口短径是促进LAAO术后PDL发生的独立危险因素(P<0.05)。 结论 CT左心耳成像可以显示术后封堵器的位置以及PDL发生情况,LAA开口参数与封堵器尺寸均呈正相关,较小的年龄、较大的LAA开口短径是促进LAAO术后PDL发生的独立危险因素。
关键词:  CT左心耳成像  房颤  左心耳封堵术  器械周围残余分流  左心耳开口
DOI:
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基金项目:
Correlation of Left Atrial Appendage opening parameters determined by preoperative CT Left Atrial Appendage imaging in patients with atrial fibrillation with the size of the occluders placed during Left Atrial Appendage Occlusion and analysis of the factors influencing the occurrence of peri‐device leak around instruments
Shanxi Medical University
Abstract:
[Abstract] Objective To analyze the correlation between the left atrial appendage (LAA) opening parameters determined by preoperative computed tomography (CT) left atrial appendage imaging in patients with atrial fibrillation (AF) and the size of the placed occluders during Left Atrial Appendage Occlusion (LAAO), and the factors influencing the occurrence of peri‐device leak (PDL) in the postoperative period. Methods To retrospectively analyze the clinical data of 83 patients with nonvalvular AF who successfully implemented LAAO from January 2019 to December 2022 in the Second Hospital of Shanxi Medical University. They were divided into PDL group (23 cases) and no-PDL group (60 cases) according to the occurrence of PDL after surgery. Clinical data and LAA opening parameters were compared between the two groups. Pearson correlation was used to analyze the association between LAA opening parameters and the size of the placed occluders intraoperatively in LAAO.Logistic regression was used to analyze the risk factors for developing PDL after LAAO. Results The age of patients in the PDL group was significantly younger than that of the no-PDL group (P < 0.05), and the differences between the two groups in terms of gender and comorbid underlying diseases were not statistically significant (P > 0.05). The long diameter, short diameter, circumference, and area of the LAA opening in the PDL group were greater than those in the no-PDL group, and the difference was statistically significant (P < 0.05).Pearson correlation analysis showed that the long diameter, short diameter, circumference, and area of the LAA opening in the no-PDL group were positively correlated with the size of the placed occluders (P < 0.05).The results of multivariate logistic regression analysis showed that younger age and larger short diameter of LAA opening were independent risk factors promoting the occurrence of PDL after LAAO (P < 0.05). Conclusion CT left atrial appendage imaging can show the position of the postoperative occluders as well as the occurrence of PDL, and all LAA opening parameters are positively correlated with occluders size, with younger age and larger short diameter of LAA opening being independent risk factors promoting the occurrence of PDL after LAAO.
Key words:  CT left atrial appendage imaging  Atrial fibrillation  Left Atrial Appendage Occlusion  Peri‐device leak  Left atrial appendage opening