引用本文:王 莉,李新剑,吴 野,仇爱珍,张梦然.重复外周磁刺激联合常规康复训练对痉挛型双瘫患儿A型肉毒毒素治疗后下肢运动功能的影响[J].中国临床新医学,2025,18(4):425-429.
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重复外周磁刺激联合常规康复训练对痉挛型双瘫患儿A型肉毒毒素治疗后下肢运动功能的影响
王 莉,李新剑,吴 野,仇爱珍,张梦然
徐州医科大学附属徐州儿童医院儿童康复科,徐州 221000
摘要:
[摘要] 目的 观察重复外周磁刺激(rPMS)联合常规康复训练对痉挛型双瘫患儿A型肉毒毒素(BoNT-A)治疗后下肢运动功能的影响。方法 招募2023年6月至2024年6月徐州医科大学附属徐州儿童医院收治的60例痉挛型双瘫患儿。患儿入组后均接受BoNT-A治疗。采用随机数字表法将患儿分为观察组(行rPMS联合常规康复训练)和对照组(行常规康复训练),各30例。分别在BoNT-A治疗前和康复治疗3个月后采用儿童平衡量表(PBS)评估患儿的平衡功能,采用粗大运动功能测试量表-88(GMFM-88)D功能区评分、E功能区评分评估患儿的下肢运动功能,采用1 min步行实验(1MWT)评估患儿的步行能力。结果 BoNT-A治疗前,两组PBS评分、1 min步行距离以及GMFM-88 D功能区评分、E功能区评分、总分比较差异无统计学意义(P>0.05)。康复治疗3个月后,两组PBS评分和GMFM-88 D功能区评分、E功能区评分及总分高于BoNT-A治疗前,且观察组高于对照组,两组1 min步行距离长于BoNT-A治疗前,且观察组长于对照组,差异有统计学意义(P<0.05)。结论 痉挛型双瘫患儿在BoNT-A治疗后辅以rPMS联合常规康复训练,可提高步行稳定性,改善下肢运动功能。
关键词:  脑性瘫痪  痉挛型双瘫  重复外周磁刺激  核心肌群  A型肉毒毒素  下肢运动功能
DOI:10.3969/j.issn.1674-3806.2025.04.13
分类号:
基金项目:徐州医科大学附属徐州儿童医院儿童康复科,徐州 221000
Effects of repetitive peripheral magnetic stimulation combined with conventional rehabilitation training on lower limb motor function after treatment of botulinum toxin type A in children with bilateral spastic cerebral palsy
WANG LI, LI Xinjian, WU Ye, QIU Aizhen, ZHANG Mengran
Department of Children′s Rehabilitation, Xuzhou Children′s Hospital Affiliated to Xuzhou Medical University, Xuzhou 221000, China
Abstract:
[Abstract] Objective To observe the effects of repetitive peripheral magnetic stimulation(rPMS) combined with conventional rehabilitation training on lower limb motor function after treatment of botulinum toxin type A(BoNT-A) in children with bilateral spastic cerebral palsy. Methods Sixty pediatric patients with bilateral spastic cerebral palsy who were admitted to Xuzhou Children′s Hospital Affiliated to Xuzhou Medical University from June 2023 to June 2024 were recruited. All the pediatric patients were treated with BoNT-A after enrollment. The pediatric patients were divided into observation group(undergoing rPMS combined with conventional rehabilitation training) and control group(undergoing conventional rehabilitation training) by using random number table method, with 30 cases in each group. The pediatric patients′ balance function was assessed by using Pediatric Balance Scale(PBS) scores, and their lower limb motor function was assessed by using the Gross Motor Function Measure-88 Dimensions D and E(GMFM-88 D/E) scores, and their walking ability was assessed by using 1-Minute Walk Test(1MWT) before treatment of BoNT-A and 3 months after rehabilitation therapy, respectively. Results Before treatment of BoNT-A, there were no significant differences in PBS scores, 1-minute walking distance, GMFM-88 D/E scores and total scores between the two groups(P>0.05). After 3 months of rehabilitation therapy, the PBS scores, GMFM-88 D/E scores and total scores in both groups were higher than those before treatment of BoNT-A, and the PBS scores, GMFM-88 D/E scores and total scores in the observation group were higher than those in the control group, and the 1-minute walking distance in both groups was longer than that before treatment of BoNT-A, and the 1-minute walking distance in the observation group was longer than that in the control group, with statistically significant differences between the two groups(P<0.05). Conclusion After treatment of BoNT-A, the pediatric patients with bilateral spastic cerebral palsy who are assisted with rPMS combined with conventional rehabilitation training can get the improvement in their walking stability and lower limb motor function.
Key words:  Cerebral palsy  Bilateral spastic cerebral palsy  Repetitive peripheral magnetic stimulation(rPMS)  Core muscles  Botulinum toxin type A(BoNT-A)  Lower limb motor function