| 摘要: |
| ［摘要］ 目的 提高临床医生对肺诺卡菌病的的认识。方法 分析4例肺诺卡菌病的临床特点，并复习相关文献。结果 4例肺诺卡菌病患者2例有免疫性疾病并服用免疫抑制剂，4例均有咳嗽咳痰和发热，3例为午后发热。肺部影像学表现4例肺实变影，3例大小不等的结节影/肿块影并可见空洞。病原学检查标本多种。磺胺治疗效果较好。结论 肺诺卡菌病缺乏特异性临床表现，肺部多发结节影/肿块影并空洞形成是其影像学特点，磺胺是主要治疗药物。 |
| 关键词: 诺卡菌感染 诊断 磺胺 |
| DOI： |
| 分类号:R 519.1 |
| 基金项目:广西壮族自治区科技厅攻关项目（桂科攻0816004-9） |
|
| Pulmonary nocardiosis: a report of 4 cases and review |
|
QIN Zhi-qiang, LV Jing, LONG Sheng-ze
|
|
Department of Respiratory Disease, the People′s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China
|
| Abstract: |
| ［Abstract］ Objective To enhance the knowledge of pulmonary nocardiosis which is an infrequent infectious disease and usually misdiagnosed during clinical practice.Methods The clinical data of 4 patients with pulmonary nocardiosis were analyzed and related literatures were reviewed. Results Two of 4 patients with pulmonary nocardiosis were suffering from autoimmune diseases and were receiving corticosteroid therapy. All of the patients had productive cough and fever, of them 3 patients had afternoon or night fever. The radiographic picture included multilobar consolidation (4/4), pleural effusion (4/4) and multiple cavitary masses (3/4). The patients were good responsive to trimethoprim-sulfamethoxazole or combination of the third generation cephalosporins. Conclusion The clinical data of pulmonary nocardiosis are non-specific. Multiple cavitary masses are the predominant radiological patterns. Cotrimoxazole is the most commonly used empirical treatment. |
| Key words: Nocardia infection Diagnosis Sulfanilamide |
