引用本文:苏素花,蒋东方,农 康,廖瑞庆.铅性肾损害效应生物标志物β2-MG、NAG、RBP的相关影响因素研究[J].中国临床新医学,2009,2(12):1239-1242.
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铅性肾损害效应生物标志物β2-MG、NAG、RBP的相关影响因素研究
苏素花,蒋东方,农 康,廖瑞庆
530021 南宁,广西壮族自治区职业病防治研究院
摘要:
[摘要] 目的 研究β2-MG、NAG、RBP在铅性肾损害评价中的影响因素。方法 采用相关分析或分组比较法。结果 β2-MG、NAG、RBP与年龄、接铅工龄呈明显正相关(r依序为:0.221、0.230、0.433,0.359、0.419、0.365),β2-MG、RBP与血铅呈明显正相关(r依序为:0.419、0.354);另外三个指标间也有明显相关关系。结论 应用RBP、β2-MG、NAG评价铅性肾损害时,应注意个体的年龄、接铅工龄的影响,并注意与血铅及其各指标间的相互关系。
关键词:  铅性肾损害  β2-MG  NAG  RBP  影响因素
DOI:10.3969/j.issn.1674-3806.2009.12.05
分类号:R 595.2
基金项目:广西壮族自治区科学技术厅自然基金项目(编号:200104)
Study on the influential factors of the β2-MG、NAG and RBP evaluating the nephrotoxicity caused by lead
SU Su-hua, JIANG Dong-fang, NON Kang, et al.
Guangxi Intitute of Occupational Disease, Nanning 530021, China
Abstract:
[Abstract] Objective To study the influential factors of the β2-MG、NAG and RBP evaluating the nephrotoxicity caused by lead.Methods In the study, the methods of the correlation analysis and group comparison were adopted.Results The data of the β2-MG, NAG and RBP are related to the age and receptive-lead standing (r: 0.221、0.230、0.433,0.359、0.419、0.365).And the data of β2-MG and RBP related to the PbB (r: 0.419、0.354).Moreover, the relations among the β2-MG、NAG and RBP were existing.Conclusion When the β2-MG, NAG and RBP are used to evaluate the nephrotoxicity caused by lead, the indexes are influenced by the age, receptive-lead standing and PbB.
Key words:  Nephrotoxicity caused by lead  β2-MG  NAG  RBP  Influential factors