摘要: |
[摘要] 黄芩苷(baicalin,C21H18O11),是从唇形科植物黄芩(scutellaria baicalensis georgi)的干燥根中提取的一种黄酮类化合物。黄芩苷是黄芩的主要有效成分,具有多种药理作用,如清热解毒、抑菌抗炎、拮抗钙离子、清除自由基、抗内毒素休克、调节免疫、降压、保肝利胆、抗变态反应和抗脂质过氧化等。近年来,动物实验和临床研究均证实,黄芩苷具有抗纤维化及器官保护作用。 |
关键词: 黄芩苷 纤维化 |
DOI:10.3969/j.issn.1674-3806.2010.03.37 |
分类号:R 593 |
基金项目: |
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The effects of baicalin on anti-fibrosis |
ZHANG Ling-ling,GUO Ming-hao
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Department of Kidney Internal Medicine,the First Affiliated Hospital of Xinxiang Medical College,Weihui Henan 453100,China
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Abstract: |
[Abstract] Baicalin(C21H18O11) is a kind of falconoid compound, extracted from dried root of Labiatae skullcap (scutellaria baicalensis georgi). Baicalin is the main active ingredient and has a variety of pharmacological effects, such as heat-clearing and detoxifying, antibacterial and anti-inflammatory, antagonizing calcium, clearing free radicals, anti-endotoxin shock, regulating immunity, adjusting blood pressure, protecting liver and cholagogic effect, anti-allergy and anti-lipid peroxidation, and so on. In recent years, animal experiments and clinical studies have confirmed that baicalin has the effects of anti-fibrosis and organ protection. |
Key words: Baicalin Fibrosis |