引用本文:罗戈南,闫立群.血必净注射液治疗烧伤并发脓毒症患者的疗效观察[J].中国临床新医学,2010,3(8):744-746.
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血必净注射液治疗烧伤并发脓毒症患者的疗效观察
罗戈南,闫立群
266042 山东,青岛公安消防医院(罗戈南);266071 山东,青岛海军潜艇学院(闫立群)
摘要:
[摘要] 目的 观察血必净注射液对烧伤脓毒症患者的抗炎作用。方法 将120例烧伤脓毒症患者随机分为治疗组与对照组,均给予常规治疗,治疗组在此基础上给予血必净注射液100 ml静脉滴注,2次/d,连用7 d,观察两组治疗前后外周血降钙素原(PCT)、C-反应蛋白(CRP)和WBC水平变化及并发症的发生情况。结果 治疗组治疗后外周血PCT、CRP和WBC水平明显下降,而对照组则变化不大,治疗组并发症发生率明显低于对照组。结论 血必净注射液对炎性因子具有拮抗作用,可改善烧伤脓毒症患者的预后。
关键词:  烧伤  脓毒症  血必净注射液  抗炎作用
DOI:10.3969/j.issn.1674-3806.2010.08.17
分类号:R 644
基金项目:
Observation on the anti-inflammatory effect of xuebijing injection on the patients with burns concomitant with sepsis
LUO Ge-nan,YAN Li-qun
The Hospital of Qingdao Fire-fighting Team,Shandong 266042,China
Abstract:
[Abstract] Objective To evaluate the effecacy of xuebijing injection on patients with burns concomitant with sepsis.Methods One hundred and twenty patients with burns concomitant with sepsis were randomly divided into therapy group and control group,and both were treated with conventional therapy.The therapy group was given xuebijing injection 100 ml intravenous drip twice daily for 7 days in addition.Before and after therapy,the changes of PCT,CRP and WBC in all patients were observed.Results The levels of PCT,CRP and WBC in the therapy group were improved significantly after therapy,but the levels of PCT,CRP and WBC in the control group were non significantly changed.The incidence of complication of therapy group was lower significantly than that of the control group.Conclusion Xuebijing injection possesses antagonistic effect on inflammatory factor in sepsis,and can improve the prognosis of patients with burns concomitant with sepsis.
Key words:  Burns  Sepsis  Xuebijing injection  Anti-inflammatory effect