| 摘要: |
| ［摘要］ 目的 观察氨氯地平治疗原发性高血压的临床疗效及不良反应。 方法 选择本院近年来诊治的原发性高血压患者150例，均给予氨氯地平5 mg，1次/d，治疗2周，如血压未达到标准增至10 mg，1次/d，疗程4周。观察临床疗效和患者用药前、用药期间及用药后血压变化情况及不良反应。结果 本组显效117例（78.0%），有效21例（14.0%），无效12例（8.0%），总有效率92.0%，治疗4周后收缩压由（153.6±19.4）mmHg降至（130.6±16.2）mmHg（P<0.01）。没有明显不良反应出现。结论 氨氯地平具有较好的降压效果和依从性，是理想的降压药物，适用于原发性高血压患者长期治疗。 |
| 关键词: 氨氯地平 原发性高血压 疗效观察 |
| DOI：10.3969/j.issn.1674-3806.2010.11.30 |
| 分类号:R 544.1 |
| 基金项目: |
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| Observation on the therapeutic effect of amlodipine in 150 patients with essential hypertension |
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OU Yan-mian
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Department of Cardiology,the Third People′s Hospital of Hechi, Guangxi 547000,China
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| Abstract: |
| ［Abstract］ Objective To observe the curative effect and adverse reaction of amlodipine in treating essential hypertension.Methods One hundred and fifty patients with essential hypertension were treated with oral dose of 5 mg/d of amlodipine,the treatment lasted for 2 weeks.The dose could be increase to 10 mg/d if blood pressure did not reach the standard level,the treatment lasted for 4 weeks.Before,during and after treatment,the changes of pressure and adverse were observed.Results The results showed marked effect in 117 patients (78.0%),effectiveness in 21 patients (14.0%),no effect in 12 patients (8.0%).The total effective rate was 92.0%.The systolic pressure decreased from (153.6±19.4)mmHg before treatment to (130.6±16.2)mmHg after treatment (P<0.01).No obvions adverse reaction was found. Conclusion Amlodipine is an ideal drug which is effective in treatment of essential hypertension with good compliance. |
| Key words: Amlodipine Essential hypertension Observation of therapeutic effect |
