| 摘要: |
| ［摘要］ 目的 探讨急性颅脑损伤后患者血清中炎症相关因子的变化规律及其意义。方法 选取我院收治的急性颅脑损伤后住院治疗患者88例，动态监测患者血清中IL-10、IL-8、TNF-α的水平，并进行统计学处理。结果 急性颅脑损伤后患者的IL-10、IL-8、TNF-α的血清水平明显升高，且颅脑损伤的程度越严重，则损伤后即刻血清炎症因子的水平越高。结论 急性颅脑损伤后患者血清炎症相关因子的水平高低可以作为患者伤情评价和判断预后的有效指标。 |
| 关键词: 炎症因子 脑损伤 预后 |
| DOI：10.3969/j.issn.1674-3806.2011.03.11 |
| 分类号:R 651.1 |
| 基金项目: |
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| Dynamic changes and clinical significance of inflammatory factors in patients with acute craniocerebral injury |
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DAI Jian-ming,TAN Mei-juan,WU Zhen-hong,et al.
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Dongsheng Hospital, Zhongshan Guangdong 528414,China
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| Abstract: |
| ［Abstract］ Objective To study the dynamic changes and clinical significance of inflammatory factors in patients with acute craniocerebral injury.Methods Dynamic measurement of TNF-α,IL-8,IL-10 in 88 patients with acute craniocerebral injury were performed and the date was analyzed statistically.Results The levels of TNF-α,IL-8,IL-10 remarkably increased immediately after acute craniocerebral injury and the severer the craniocerbral injury,the higher the level of inflammatory factors.Conclusion The level of inflammatory factors in patients with acute craniocerebral injury can serve as a guideline for judging the injury degree and prognosis. |
| Key words: Acute craniocerebral injury Inflammatory factors Prognosis |
