| 摘要: |
| ［摘要］ 胰岛素受体底物(insulin receptor substrate,IRS)是胰岛素信号传导通路中受体后水平的重要信号蛋白。IRS-1对骨骼生长、骨转换以及骨折愈合等均具有重要作用，为代谢性骨病和骨质疏松的防治提供了新思路。 |
| 关键词: 胰岛素受体底物-1 骨代谢 |
| DOI：10.3969/j.issn.1674-3806.2012.08.38 |
| 分类号:R 587 |
| 基金项目: |
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| Insulin receptor substrate-1 and bone metabolism |
|
HE Yu-ling,ZHOU Hou-de
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The Metabolism and Diabetes Mellitus Research Center,the First Affiliated Hospital of Guangxi Medical University, Nanning 530021,China
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| Abstract: |
| ［Abstract］ Insulin receptor substrate (IRS ) is an important signaling proteins in insulin signal transduction pathways. IRS-1 plays an important role in skeletal growth, bone turnover and bone fracture healing. It may be a new point for the prevention and treatment of metabolic bone disease and osteoporosis. |
| Key words: Insulin receptor substrate-1 Bone metabolism |
