引用本文:袁育林,覃桂芳,杜武杰,阳文辉,赵红英,熊礼佳.随机尿 晨尿 24 h尿视黄醇结合蛋白/尿肌酐与24 h尿蛋白的相关性研究[J].中国临床新医学,2013,6(6):512-514.
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随机尿 晨尿 24 h尿视黄醇结合蛋白/尿肌酐与24 h尿蛋白的相关性研究
袁育林,覃桂芳,杜武杰,阳文辉,赵红英,熊礼佳
530021 南宁,广西壮族自治区人民医院检验科(袁育林,覃桂芳,杜武杰,阳文辉,赵红英),泌尿内科(熊礼佳)
摘要:
[摘要] 目的 研究用肌酐校正随机尿、晨尿、24 h尿视黄醇结合蛋白(URBP)后与24 h尿蛋白(UP)定量的相关性。方法 收集泌尿内科住院或门诊患者同一天内随机尿、晨尿和24 h尿标本,分别测定三种不同类型尿液中的视黄醇结合蛋白(RBP)、肌酐(Cr)以及UP含量,其中晨尿和随机尿的结果分别以肌酐比值表示。结果 24 h URBP与24 h UP的相关性为0.955(P=0.000);随机尿、晨尿URBP与24 h URBP的相关系数分别为0.663、0.707(P=0.000),与24 h UP的相关系数分别为0.673、0.738(P=0.000),其结果经尿肌酐校正后与24 h UP的相关系数分别为0.792、0.880(P=0.000)。结论 晨尿、随机尿URBP/UCr比值与24 h尿蛋白有良好的相关性,且标本收集方便易行。
关键词:  24 h尿  晨尿  随机尿  尿蛋白  尿视黄醇/尿肌酐
DOI:10.3969/j.issn.1674-3806.2013.06.02
分类号:R 446.12
基金项目:广西卫生厅科研课题(编号:Z2012258)
Correlation analysis of urinary retinal binding protein/urinary creatinine ratio in random urine, morning voiding urine and 24 h urine with 24 h urinary quantitative protein
YUAN Yu-lin, QIN Gui-fang, DU Wu-jie, et al.
Department of Clinical Laboratory, the People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021,China
Abstract:
[Abstract] Objective To study the correlations between the retinal binding protein to creatinine ratio in random urine, morning voiding urine and 24 h urine and the 24 h protein.Methods The random urine,morning voiding urine and 24 h urine of patients were collected in the same day, and retinal binding protein, microalbumin, and creatinine were detected respectively.The results of random urine and morning voiding urine should be expressed in ratios with creatinine.Results There were good correlations of 24 h urinary retinal binding protein and 24 h urinary protein. The correlation coefficient was 0.955(P=0.000). The correlation coefficients of retinal binding protein in random urine and morning voiding urine with 24 h retinal binding protein were 0.663,0.707(P=0.000),and with 24 h urinary protein were 0.673,0.738(P=0.000). The correlation coefficients of retinal binding protein/creatinine in random urine and morning voiding urine with 24 h urine protein were 0.792,0.880(P=0.000).Conclusion It is suggested that there is a significant correlation between the ratio of retinal binding protein/creatinine in random urine or morning voiding urine and 24 hour urinary quantitative protein,and both of the sample can be obtained easily.
Key words:  24 hour urine  Random urine  Morning voiding urine  Urine protein  Urinary retinal binding protein/urinary creatinine ratio