| 摘要: |
| ［摘要］ 目的 探讨手足口病患儿血清中心肌酶、超敏C反应蛋白（hs-CRP）及全血白细胞（WBC）计数的变化及临床意义。方法 选取2012-06～2013-04在该院儿科收治的重症手足口病患儿38例，选取普通手足口病患儿138例，并与30例健康对照组进行以上三个项目的检测比较分析。结果 重症手足口病患儿血清天门冬氨酸氨基转移酶(AST)活性、肌酸激酶(CK)活性、肌酸激酶同工酶(CK-MB)活性、乳酸脱氢酶(LDH)活性、α-羟丁酸脱氢酶(α-HBDH)活性、hs-CRP浓度、WBC计数及中性粒细胞百分比均显著高于健康对照组及普通患儿组(P<0.05)，普通患儿组CK活性、CK-MB活性、hs-CRP浓度、WBC计数较对照组升高，差异有统计学意义(P<0.05)。结论 联合检测心肌酶、hs-CRP及WBC计数对临床早期诊断手足口病患儿病情有较高的诊断价值。 |
| 关键词: 手足口病 心肌酶 超敏C反应蛋白 白细胞计数 |
| DOI：10.3969/j.issn.1674-3806.2014.04.12 |
| 分类号:R 446.11+2 |
| 基金项目: |
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| Clinical signficance on detection of myocardial enzymes,high sensitivity C-reactive protein and peripheral white blood cells count in children with severe hand-foot-mouth disease |
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YU Guo-qing, ZHU Xue-long
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Department of Clinical Laboratory, North Hospital of Huainan Xinhua Medical Group, Anhui 232082, China
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| Abstract: |
| ［Abstract］ Objective To evaluate the clinical significance on detection of myocardial enzymes,high sensitivity C-reactive protein(hs-CRP)and peripheral white blood cells(WBC) count in children with hand-foot-mouth disease(HFMD).Methods Thirty-eight children with severe HFMD who treated in our hospital from June 2012 to April 2013 were selected, and 138 children with mild HFMD were selected randomly, and 30 healthy children were used as control group. Serum myocardial enzymes,hs-CRP and WBC count were tested and the data were analyzed statistically.Results The levels of serum myocardial enzymes，hs-CRP and WBC in the severe group were significantly higher than those in the control group and mild group(P<0.05).The levels of serum CK，CK-MB，hs-CRP and peripheral WBC in the mild group were significantly higher than those in the control group(P<0.05).Conclusion The combined detection of myocardial enzymes,hs-CRP and WBC count could have higher value for early diagnosis and assessment of disease condition in the children with HFMD. |
| Key words: Hand-foot-mouth disease(HFMD) Myocardial enzyme High sensitivity C-reactive protein(hs-CRP) White blood cells count(WBC) |
