| 摘要: |
| ［摘要］ 目的 观察1%盐酸麻黄碱滴鼻液对高压氧治疗患者血压的影响，为高压氧治疗患者正确使用麻黄碱提供参考。方法 将60例行高压氧治疗的患者按随机数字表法分为观察组和对照组各30例。进舱治疗前观察组滴1%盐酸麻黄碱滴鼻液（每侧鼻腔3滴），对照组不滴药，分别于治疗前、加压20 min、稳压吸氧25 min、稳压吸氧50 min、减压结束前、治疗结束后30 min测量患者坐位右侧上肢血压，观察两组血压变化，并进行统计学分析。结果 加压20 min、稳压吸氧25 min、稳压吸氧50 min、减压结束前、治疗结束后30 min，观察组的收缩压和舒张压与对照组比较，差异均无统计学意义（P>0.05）。治疗过程两组血压均随时间呈先升高后下降趋势，与治疗前比较差异有统计学意义（P<0.05）。但组间与时点之间不存在交互作用，即滴药与不滴药对血压的影响是一致的。结论 对血压正常的高压氧治疗患者，进舱前少量（每侧鼻腔3滴）滴1%盐酸麻黄碱滴鼻液对血压无影响。 |
| 关键词: 麻黄碱 滴鼻液 高压氧 血压 |
| DOI：10.3969/j.issn.1674-3806.2014.09.08 |
| 分类号:R 47 |
| 基金项目:广西卫生厅科研课题（编号：Z2008046） |
|
| Impacts of nasal drop of 1% ephedrine hydrochloride on blood pressure of patients treated with hyperbaric oxygen |
|
KONG Lei, FU Gui-fen, XIE Jin-ping, et al.
|
|
Department of Hyperbaric Oxygen Therapy, the People′s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China
|
| Abstract: |
| ［Abstract］ Objective To provide a reference for proper use of ephedrine by observing impacts of nasal drop of 1% ephedrine hydrochloride on blood pressure of patients treated with hyperbaric oxygen(HPO).Methods Sixty HBO patients were randomly divided into two groups(30 cases for each), i.e. observed group and contrast group. Patients in observed group, before being sent into large medical hyperbaric oxygen tank, were put 1% ephedrine hydrochloride nasal drops three drops into bilateral nasal cavities while those in contrast group won′t. Their blood pressure were measured at the right upper limb in different period of time, i.e. before HBO, at 20 min of pressurizing, at 25 min and 50 min of oxygen inhalation under stable pressure, before finishing of decompressing, at 30 min after HBO. Their blood pressure change were observed and statistical analysis was carried out.Results For systolic pressure and diastolic pressure, there was no significant difference between observed group and contrast group(P>0.05). The blood pressure of both groups increased first and then decreased during HBO, it had statistical significance comparing with prior treatment(P<0.05). But there was no interaction between groups and time-points, that showed, impacts on blood pressure treating with or without nasal drop were the same.Conclusion For those patients who is in normal blood pressure,taking nasal drop of 1% ephedrine hydrochloride three drops into bilateral nasal cavities before HBO does not affect blood pressure. |
| Key words: Ephedrine Nasal drop Hyperbaric oxygen(HBO) Blood pressure |
