| 摘要: |
| ［摘要］ 目的 探讨患者糖化血红蛋白（HbA1c）与急性冠脉综合征发生和发展及危险严重程度的关系。方法 选取急性冠脉综合征患者526例和正常对照者82例。比较不同急性冠脉综合征类型、冠脉狭窄程度及急性冠脉综合征危险风险程度组间HbA1c水平，探讨HbA1c与急性冠脉综合征的发生发展、冠脉严重程度及危险程度的相关性。结果 ST段抬高型急性冠脉综合征（STEMI）患者和非ST段抬高型急性冠脉综合征（NSTEMI）患者HbA1c水平明显高于正常组（P<0.05）。随着冠脉病变程度不断加重，HbA1c水平逐渐增高（P<0.05）；随着冠心病危险程度不断增加，HbA1c水平逐渐增高（P<0.05）。结论 随着冠脉病变程度加重HbA1c水平呈升高趋势。血清HbA1c水平与冠心病危险程度关系密切，是急性冠脉综合征危险程度加重的因素。 |
| 关键词: 急性冠脉综合征 糖化血红蛋白 |
| DOI：10.3969/j.issn.1674-3806.2015.06.02 |
| 分类号:R 543.3 |
| 基金项目:广西科学研究与技术开发计划项目（编号：桂科攻1355005-4-6） |
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| Analysis of correlation between HbA1c and acute coronary syndrome and its risk degree |
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ZHANG Jing-jing, XU Ge
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Guangxi Medical University, Nanning 530021, China
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| Abstract: |
| ［Abstract］ Objective To explore the relationship between HbA1c and the occurrence, development and the risk degree of acute coronary syndrome(ACS).Methods 526 patients with ACS were collected as ACS group and 82 healthy people were taken as the control group. HbA1c levels were compared in different types of ACS, severities of coronary artery stenosis and the risk levels to explore the correlation between HbA1c and the occurrence, development, and the risk degree of ACS.Results HbA1c levels in both STEMI and NSTEMI patients were significantly greater in the ACS group than those in the control group（P<0.05）. HbA1c levels were gradually increased with both the constantly worsened conditions and the rising risk degrees of coronary heart diseases（P<0.05）.Conclusion HbA1c levels show a trend of increasing with the aggravation of coronary artery diseases. Serum HbA1c level is closely connected with the risk degree of coronary heart diseases, therefore, is a factor of the aggravation of the risk degree of ACS. |
| Key words: Acute coronary syndrome(ACS) HbA1c |
