摘要: |
[摘要] 目的 观察体外膜肺氧合(ECMO)治疗重症急性呼吸衰竭的临床疗效,探讨影响ECMO治疗效果的相关因素。方法 回顾性分析因重症急性呼吸衰竭接受ECMO治疗的患者32例,其中成功组25例,失败组7例。记录所有患者ECMO治疗前一般情况、ECMO期间血气分析、血流动力学以及急性生理与慢性健康状况评分Ⅱ(APACHEⅡ)等。结果 成功组患者治疗前APACHEⅡ评分明显低于失败组(P<0.05),治疗后两组患者APACHEⅡ评分均明显下降。两组患者接受ECMO治疗后心率、呼吸频率、氧合指数均较治疗前有明显改善。结论 ECMO是重症急性呼吸衰竭的有效治疗手段。APACHEⅡ是影响ECMO治疗效果的重要因素。 |
关键词: 体外膜肺氧合 呼吸衰竭 APACHEⅡ |
DOI:10.3969/j.issn.1674-3806.2016.01.17 |
分类号:R 563.8 |
基金项目: |
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Clinical experience of 32 cases with severe acute respiratory failure treated by extracorporeal membrane oxygenation |
WANG You-feng
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Department of Pediatrics, the First People′s Hospital of Nanyang,Henan 473000,China
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Abstract: |
[Abstract] Objective To observe the efficacy of extracorporeal membrane oxygenation(ECMO) treatment on severe acute respiratory failure, and to explore the factors associated with prognosis.Methods Thirty-two patients with severe acute respiratory failure treated by ECMO were retrospectively analyzed, among whom 25 patients were successfully treated(success group) and 7 patients failed(failure group). General conditions prior to ECMO, blood gas analysis, hemodynamics, acute physiology and chronic health evaluation Ⅱ(APACHEⅡ) scores during ECMO of all patients were recorded.Results The APACHE Ⅱ scores prior to ECMO of patients in success group were lower than those in failure group(P<0.05). The APACHEⅡ scores of both groups were significantly decreased after ECMO. Heart rate, respiratory rate and oxygenation index of patients in both groups were significantly improved after ECMO.Conclusion VV-ECMO is an effective treatment for severe acute respiratory failure. APACHE Ⅱ score is an important factor that affects the ECMO efficacy. |
Key words: Extracorporeal membrane oxygenation(ECMO) Respiratory failure APACHEⅡ |