| 摘要: |
| ［摘要］ Graves病（GD）是自身免疫性甲状腺疾病，文献中偶有GD伴有肾损害的报道。由于肾病起病隐匿很难发现，而GD患者平时主要在甲状腺疾病专科就诊，患者往往出现明显的临床症状或肾功能不全后才到肾脏病专科就诊。GD相关性肾病发病机制还不清楚，治疗还没得到共识。该文就GD相关性肾病的临床表现、发病机制及诊断治疗作一综述，以便能更好地认识GD相关肾病，提早诊断和干预治疗。 |
| 关键词: Graves病 自身免疫性疾病 肾病 蛋白尿 放射性碘131 |
| DOI：10.3969/j.issn.1674-3806.2016.01.28 |
| 分类号:R 581 |
| 基金项目: |
|
| Research progress in Graves′disease-associated nephrotic |
|
HUANG Wen-tan, GONG Zhi-feng
|
|
Department of Nephrology, the People′s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China
|
| Abstract: |
| ［Abstract］ Graves′disease(GD) is an autoimmune thyroid disease and a few of GD associated with kidney injury were reported in the literatures. As kidney disease with concealed onset is hard to find, and GD patients mainly visit thyropathy doctors in normal time, the patients will not go to see nephrologists until the definite clinical symptoms or renal insufficiency occur. The pathogenesis of GD-associated nephrotic is not clear and no consensus has been reached on the treatment for the disease. In order to better understand GD-associated nephrotic,diagnosis in the early stage and intervention treatments, the clinical manifestations, pathogenesis, diagnosis and the treatments of this disease are reviewed in this paper. |
| Key words: Graves′ diseases Autoimmune diseases Nephrotic Proteinuria Radioactive iodine 131 |
