引用本文:甘海球,简卓欢,唐华峰,李洪双,蒋伟伦.小金瓜散对提高幽门螺杆菌根除率的临床价值[J].中国临床新医学,2016,9(4):288-290.
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小金瓜散对提高幽门螺杆菌根除率的临床价值
甘海球,简卓欢,唐华峰,李洪双,蒋伟伦
528429 广东,中山市黄圃人民医院中医康复科
摘要:
[摘要] 目的 探讨标准三联疗法同小金瓜散结合治疗对提高幽门螺杆菌(Hp)根除率的临床效果。方法 选取2014-07~2015-07收治因Hp感染引起的慢性胃炎患者75例为研究对象,采用随机数字表法,分为A组25例,给予标准三联疗法治疗;B组25例,在西医基础上加用小金瓜散剂治疗;C组25例,在西医基础上加用小金瓜汤剂治疗,均治疗2周,停药30 d后,观察三组患者Hp根除情况及用药依从情况。结果 经治疗,B、C两组患者Hp根除率分别为88.0%和84.0%,高于A组的72.0%(P<0.01),B组Hp根除率与C组比较差异无统计学意义(P>0.05)。A、B、C三组用药依从率分别为92.0%、88.0%、84.0%,差异无统计学意义(P>0.05)。结论 在标准三联疗法中应用小金瓜散,可提高Hp根除率,且使用方便,口感较好,患者接受度高,值得推广。
关键词:  慢性胃炎  幽门螺杆菌  小金瓜散  临床效果
DOI:10.3969/j.issn.1674-3806.2016.04.04
分类号:R 573
基金项目:广东省中山市医学科研项目(编号:2015A020118)
Clinical value of Xiaojingua powder in eradication of Helicobacter pylori
GAN Hai-qiu, JIAN Zhuo-huan, TANG Hua-feng, et al.
Department of Rehabilitation Medicine, the People′s Hospital of Huangpu, Zhongshan City, Guangdong 528429, China
Abstract:
[Abstract] Objective To investigate the clinical effect of standard triple therapy combined with Xiaojingua powder in eradication of Helicobacter pylori(Hp).Methods Seventy-five patients with chronic gastritis caused by HP in our hospital from July 2014 to July 2015 were divided into three groups according to the random number table method. Group A(n=25) was given the standard triple therapy; group B(n=25) and group C(n=25) were treated with oral Xiaojingua powder based on the treatment of western medicine. The eradication of Hp and compliance of the drug use were compared among the three groups two weeks after the treatment and thirty days after the discontinuation of medicine.Results After the treatment, the eradication rates in both group B(88%) and group C(84%) were significantly higher than that in group A(72%)(P<0.01). There was no significant difference in the eradication of Hp between group B and group C(P>0.05). The medication compliance rates were 92%, 88% and 84% in group A, group B and group C, without significant differences among the three groups(P>0.05).Conclusion Xiaojingua powder in combination with the standard triple therapy is convenient in use and increases the eradication rate of Hp in patients with chronic gastritis.
Key words:  Chronic gastritis  Helicobacter pylori(HP)  Xiaojingua powder  Clinical effect