| 摘要: |
| ［摘要］ 目的 探讨早期姑息治疗在晚期转移性乳腺癌初治中的临床意义。方法 选取2011-07～2014-12该院收治的首诊转移性乳腺癌患者53例，随机分为治疗组27例和对照组26例。治疗组采用早期姑息治疗加标准化疗，对照组仅采用标准化疗。两组患者治疗前后均接受医院焦虑抑郁量表（HADS）和病人健康问卷（PHQ-9）评估，并观察两组患者总生存期。结果 治疗组HADS（D）和PHQ-9评分降低程度明显大于对照组，差异有统计学意义（P<0.05）。治疗组和对照组中位总生存时间分别为29.0个月和23.5个月，差异有统计学意义（P<0.05）。结论 早期姑息治疗可提高转移性乳腺癌患者生存质量，延长生存期。 |
| 关键词: 转移性乳腺癌 初治 姑息治疗 |
| DOI：10.3969/j.issn.1674-3806.2016.05.13 |
| 分类号:R 737.9 |
| 基金项目: |
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| The clinical significance of early palliative care in previously untreated patients with advanced metastatic breast cancer |
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SHAN Feng-xiao, REN Tie-jun
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Department of Oncology, Luoyang Center Hospital Affiliated to Zhengzhou University, Henan 471009, China
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| Abstract: |
| ［Abstract］ Objective To observe the clinical significance of early palliative care in previously untreated patients with advanced metastatic breast cancer.Methods Fifty-three patients with metastatic breast cancer confirmed by pathology and imaging were collected from July 2011 to December 2014, and were randomly divided into two groups. The treatment group(n=27) received early palliative care and standard chemotherapy, while the control group(n=26) was treated with chemotherapy alone. The levels of Hospital Anxiety and Depression Scale(HADS) and the Patient Health Questionnaire(PHQ-9) were compared between the two groups before and after the treatment, and the overall survival was also observed.Results HADS(D) and PHQ-9 scores in the treatment group were significantly lower than those in the control group(P<0.05). The median overall time of the treatment group(29.0 months) was significantly longer than that of the control group(23.5 months)(P<0.05).Conclusion Early palliative care improves the quality of life in patients with metastatic breast cancer, and prolongs their overall survival. |
| Key words: Metastatic breast cancer Initial treatment Early palliative care |
