| 摘要: |
| ［摘要］ 目的 观察经鼻双水平气道正压通气（BiPAP）治疗早产儿呼吸暂停的临床效果。方法 选择62例符合原发性早产儿呼吸暂停诊断患儿随机分为对照组和研究组，各31例。对照组在常规治疗基础上采用鼻塞持续气道正压通气（CPAP）进行呼吸支持，研究组在常规治疗基础上采用鼻塞BiPAP进行呼吸支持，两组治疗无效则予气管插管进行机械通气治疗。观察两组患儿呼吸暂停缓解率、住院时间、用氧总时间、治疗无效后气管插管率及并发症发生率。结果 研究组呼吸暂停缓解率为61.3%，高于对照组的35.5%（P<0.05）；治疗无效后气管插管率为9.7%，低于对照组的32.3%（P<0.05）。两组住院时间、用氧总时间及气漏、腹胀、鼻压伤、颅内出血并发症差异无统计学意义（P>0.05）。结论 经鼻BiPAP治疗早产儿呼吸暂停疗效显著、安全，值得推广。 |
| 关键词: 经鼻双水平气道正压通气 早产儿 呼吸暂停 临床效果 |
| DOI：10.3969/j.issn.1674-3806.2016.05.14 |
| 分类号:R 722 |
| 基金项目: |
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| Clinical application of nasal bilevel positive airway pressure ventilation on treating apnea of prematurity |
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ZHAO Quan-en, LIAO Pei-chan
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Department of Pediatrics, the Second People′s Hospital of Xinhui District of Jiangmen City, Guangdong 529100, China
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| Abstract: |
| ［Abstract］ Objective To study the clinical effect of nasal bilevel positive airway pressure ventilation on treating apnea of prematurity.Methods Sixty-two premature infants with primary apnea were randomly divided into the control group and the study group, with 31 cases in each group. The control group was given nCPAP and the study group was given nBiPAP on the basis of the routine treatment. If the treatment was not effective in the two groups, endotracheal intubation and mechanical ventilation were used. The remission rate of apnea, the hospitalization time, the total time of using oxygen, the rate of endotracheal intubation and the complications were compared between the two groups.Results The remission rate of apnea of prematurity in the study group(61.3%) was higher than that in the control group(35.5%). The rate of endotracheal intubation in the study group(9.7%) was lower than that in the control group(32.3%)(P<0.05). There were no signficant differences in the hospitalization time, the total time of using oxygen, pneumothorax, abdominal distention, nasal skin damage and intracranial hemorrhage between the two groups(P>0.05).Conclusion Nasal bilevel positive airway pressure ventilation is safe and effective on treating apnea of prematurity. |
| Key words: Nasal bilevel positive airway pressure ventilation Premature infant Apnea Clinical effect |
