| 摘要: |
| ［摘要］ 目的 观察小剂量肾上腺素加异丙肾上腺素治疗毛细支气管炎的效果。方法 选取毛细支气管炎患者98例，随机分为两组各49例。观察组采用小剂量肾上腺素联合异丙肾上腺素治疗，对照组采用氨茶碱治疗。比较两组治疗后临床症状消失时间、肺功能及临床疗效。结果 观察组发绀消失、喘憋消失、咳嗽消失、湿啰音消失及住院时间均少于对照组，吸呼比（Ti/Te）也明显低于对照组，而潮气量、达峰时间比（TPTEF/TE）、达峰容积比（VPEF/VE）则高于对照组，两组差异有统计学意义（P均<0.01）。观察组显效27例，有效20例，无效2例，对照组显效20例，有效18例，无效11例，组间比较差异有统计学意义（P<0.05）。结论 小剂量肾上腺素联合异丙肾上腺素可快速缓解毛细支气管炎患儿喘憋、呼吸困难症状，改善肺功能，安全有效，值得临床推广应用。 |
| 关键词: 毛细支气管炎 小剂量肾上腺素 异丙肾上腺素 |
| DOI：10.3969/j.issn.1674-3806.2016.08.15 |
| 分类号:R 725.6 |
| 基金项目: |
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| Clinical application study of a small dose of adrenaline combined with isoproterenol on bronchiolitis |
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LIU Yuan-lin
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Clinical application study of a small dose of adrenaline combined with isoproterenol on bronchiolitis
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| Abstract: |
| ［Abstract］ Objective To study the effect of a small dose of adrenaline combined with isoproterenol on the treatment of bronchiolitis.Methods Ninety-eight bronchiolitis patients were randomly divided into two groups, with 49 cases in each group. The observation group was given a small dose of adrenaline combined with isoproterenol, and the control group was given theophylline. The clinical symptoms disappeared time, pulmonary function and clinical efficacy after the treatment were compared between the two groups.Results The cyanosis disappearance time, wheezing disappearance time, cough disappearance time, moist rale disappearance time and hospital stay of the observation group were less than those of the control group. The respiration ratio(Ti/Te) was significantly lower in the observation group than that in the control group, P<0.01; while tidal volume, TPTEF/TE and VPEF/VE were significantly higher in the observation group than those in the control group(P<0.01); 27 cases were markedly effective, 20 cases effective, 2 cases invalid in the observation group, while 20 cases were markedly effective,18 cases effective, 11 cases invalid in the control group, with a significant difference between the two groups(P<0.05).Conclusion Low-dose epinephrine and isoproterenol can be safe and effective to relieve bronchiolitis wheezing quickly, and dyspnea and improve the lung function. |
| Key words: Bronchiolitis Small dose of epinephrine Isoproterenol |
