| 摘要: |
| ［摘要］ 网膜素-1主要由内脏脂肪分泌，是具有抗炎、抗氧化应激、抗动脉粥样硬化、增加胰岛素敏感性及舒张血管作用的新型脂肪因子。研究发现其在心血管疾病、糖脂代谢紊乱、胰岛素抵抗及肥胖症等患者体内表达较正常人群降低，而在有氧运动和体重减轻后表达升高。网膜素-1未来可能成为防治心血管相关疾病的新靶点。 |
| 关键词: 网膜素-1 心血管疾病 内脏脂肪 糖代谢异常 |
| DOI：10.3969/j.issn.1674-3806.2016.12.33 |
| 分类号:R 54 |
| 基金项目:广西科学研究与技术开发计划项目（编号：桂科攻1598012-7）；广西医疗卫生适宜技术研究与开发项目（编号：S201422-05） |
|
| The research progress of omentin-1 and cardiovascular disease related factors |
|
JIANG Ling-yun, YAN Xiao-dong
|
|
Department of Endocrinology, Guangxi University of Traditional Chinese Medicine, Nanning 530021, China
|
| Abstract: |
| ［Abstract］ Omentin-1 is mainly excreted by visceral adipose tissue, which has the actions of anti-inflammatory, anti-oxidant, anti-atherosclerosis, increasing insulin sensitivity and dilating blood vessels. The expression of omentin-1 in the patients who have cardiovascular diseases, glucose and lipid metabolism disorders, insulin resistance or obesity is lower than that in the normal population in many studies, however it will elevate after aerobic exercise and weight loss. Omentin-1 may become a new target for the prevention and treatment of cardiovascular related diseases in the future. |
| Key words: Omentin-1 Cardiovascular disease Visceral adipose tissue Hyperglycemia |
