| 摘要: |
| ［摘要］ 目的 探讨内镜下蓝激光成像（blue laser imaging，BLI）技术与碘染色对多原发食管癌的诊断价值。方法 选取2015-06～2018-08在广西壮族自治区人民医院消化内镜中心经病理诊断为食管癌的437例患者，对比内镜下BLI与碘染色对多原发食管癌的诊断价值。结果 经病理证实的多原发食管癌共47例，占所有食管癌患者的10.75%（47/437）；共检出癌灶99个，分布于食管上段24个，中段58个，下段17个；早期食管癌27个，进展期食管癌72个。BLI诊断多原发食管癌的灵敏度、特异度分别为89.36%、99.49%。碘染色诊断多原发食管癌的灵敏度、特异度分别为95.74%、98.97%。BLI和碘染色在诊断多原发食管癌上与病理诊断具有较高的一致性（Kappa=0.914；Kappa=0.930）。但是BLI与碘染色对多原发食管癌的检出率比较差异无统计学意义（P>0.05）。结论 内镜下BLI与碘染色对多原发食管癌均有较高的诊断价值。 |
| 关键词: 食管肿瘤 多原发性 碘染色 蓝激光成像 |
| DOI：10.3969/j.issn.1674-3806.2019.07.07 |
| 分类号:R 735.1 |
| 基金项目:广西卫健委科研课题（编号：Z20170358） |
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| A comparative study of endoscopic blue laser imaging and iodine staining in diagnosis of multiple primary esophageal carcinoma |
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YI Nan, NONG Bing, ZHANG Wen-hua, et al.
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Department of Gastroenterology, the People′s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China
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| Abstract: |
| ［Abstract］ Objective To investigate the diagnostic value of endoscopic blue laser imaging(BLI) technology and iodine staining for multiple primary esophageal carcinoma. Methods Four hundred and thirty-seven patients who were pathologically diagnosed with esophageal cancer at the Digestive Endoscopy Center of the People′s Hospital of Guangxi Zhuang Autonomous Region from June 2015 to August 2018 were selected. The diagnostic value of endoscopic BLI and iodine staining for multiple primary esophageal carcinoma was compared. Results A total of 47 cases of multiple primary esophageal cancer were confirmed by pathology, accounting for 10.75%(47/437) of all the esophageal cancer patients. Ninety-nine lesions were detected, including 24 in the upper esophagus, 58 in the middle and 17 in the lower esophagus. There were 27 cases of early esophageal cancer and 72 cases of advanced esophageal cancer. The sensitivity and specificity of BLI in diagnosis of multiple primary esophageal cancer were 89.36% and 99.49%, respectively. The sensitivity and specificity of iodine staining in diagnosis of multiple primary esophageal cancer were 95.74% and 98.97%, respectively. BLI and iodine staining under endoscopy had good consistency with pathological diagnosis in diagnosis of multiple primary esophageal carcinom(Kappa=0.914,Kappa=0.930). However, there was no significant difference in the detection rate of multiple primary esophageal carcinoma between BLI and iodine staining(P>0.05). Conclusion Both BLI and iodine staining under endoscopy have high diagnostic value for multiple primary esophageal carcinoma. |
| Key words: Esophageal carcinoma Multiple primary Iodine staining Blue laser imaging(BLI) |
