引用本文:郭玲玲,杨志清,王海星,张 靓,郭燕青,郝崇奇,齐 昊.妊娠期发生高血压疾病的危险因素分析[J].中国临床新医学,2020,13(5):466-470.
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妊娠期发生高血压疾病的危险因素分析
郭玲玲,杨志清,王海星,张 靓,郭燕青,郝崇奇,齐 昊
030001 太原,山西医科大学第一医院医疗大数据中心(郭玲玲,杨志清,王海星,张 靓,郭燕青,郝崇奇),内分泌科(齐 昊)
摘要:
[摘要] 目的 探讨妊娠期高血压疾病(HDCP)的危险因素,为预防HDCP提供理论依据。方法 选择2006-06~2017-06在该院产科住院分娩的980例孕妇作为研究对象,根据HDCP的发生情况将其分为HDCP组(n=141)和非HDCP组(n=839)。基于该院医疗大数据平台,收集研究对象的一般人口学特征、生育史、家族史、疾病史及产前血钙水平等资料,采用Logistic回归分析HDCP发生的危险因素。结果 HDCP发生率为14.39%(141/980)。HDCP组母亲年龄≥35岁、孕妇体质量指数(BMI)≥24.0 kg/m2、母亲(或姐妹)有高血压疾病史及合并低血钙水平的人数比例大于非HDCP组,差异有统计学意义(P<0.05)。Logistic回归分析结果显示,孕妇BMI≥24.0 kg/m2、母亲(或姐妹)有高血压疾病史及合并低血钙是孕妇发生HDCP的危险因素。结论 孕妇BMI、家族高血压疾病史及血钙水平降低与HDCP的发生密切相关,在妊娠期定期监测血钙水平的同时应加强孕妇孕期及分娩期风险识别与管理。
关键词:  妊娠期高血压疾病  危险因素  血钙
DOI:10.3969/j.issn.1674-3806.2020.05.09
分类号:R 714.24+6
基金项目:山西省重点研发计划项目(编号:201803D31099)
Analysis of risk factors of hypertensive disorder complicating pregnancy
GUO Ling-ling, YANG Zhi-qing, WANG Hai-xing, et al.
Medical Large Data Center, First Hospital of Shanxi Medical University, Taiyuan 030001, China
Abstract:
[Abstract] Objective To explore the risk factors of hypertensive disorder complicating pregnancy(HDCP) and to provide a theoretical basis for prevention of HDCP. Methods Nine hundred and eighty pregnant women who gave birth in the obstetrics department of our hospital from June 2006 to June 2017 were selected as the research subjects. They were divided into HDCP group(n=141) and non-HDCP group(n=839) according to whether or not HDCP occurred. Based on the hospital′s medical large data platform, the general demographic characteristics, fertility history, family history, disease history, and prenatal blood calcium levels of the study subjects were collected. Logistic regression was used to analyze the risk factors of HDCP. Results The incidence of HDCP was 14.39%(141/980). The proportion of the mothers in the HDCP group with age ≥35 years, the body mass index(BMI) during pregnancy ≥24.0 kg/m2, and the mothers(or their sisters) having a history of hypertension and low blood calcium levels was larger than that in the non-HDCP group, and the difference was statistically significant between the two groups(P<0.05). Logistic regression analysis showed that pregnant women with BMI ≥24.0 kg/m2, mothers(or their sisters) with a history of hypertension and hypocalcemia were the risk factors of HDCP in pregnant women. Conclusion BMI, a family history of hypertension and decreased blood calcium level are closely related to the occurrence of HDCP in pregnant women. The risk identification and management of pregnant women during pregnancy and delivery should be strengthened while the blood calcium level is regularly monitored during pregnancy.
Key words:  Hypertensive disorder complicating pregnancy(HDCP)  Risk factors  Blood calcium