| 摘要: |
| ［摘要］ 目的 探讨乳腺癌超声造影增强模式特征与分子生物学指标及腋窝淋巴结转移的关联。方法 回顾性分析109例乳腺癌女性患者的超声造影特征与病历资料，分析超声造影增强模式特征（增强顺序、增强强度、充盈缺损、放射汇聚、超范围）与分子生物学指标、乳腺癌腋窝淋巴结转移的关联性。结果 109例患者共109个肿块中，超声造影显示有充盈缺损68例，病理结果诊断有腋窝淋巴结转移64例，Kappa一致性检验显示两者具有较好的一致性（Kappa=0.732）。超声造影的充盈缺损征象诊断腋窝淋巴结转移的灵敏度为92.19%，特异度为83.33%。结论 乳腺癌超声造影充盈缺损征象与腋窝淋巴结转移有一定关联，可对乳腺癌的预后评估有一定的指导作用。 |
| 关键词: 乳腺癌 超声造影增强模式特征 分子生物学指标 腋窝淋巴结 |
| DOI：10.3969/j.issn.1674-3806.2019.08.11 |
| 分类号:R 445 |
| 基金项目:广西科学研究与技术开发计划项目（编号：桂科攻14124004-1-13） |
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| Study on correlation between characteristics of contrast-enhanced ultrasonography and prognostic factors of breast cancer |
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ZHOU Chun-qiao, WANG Xiao-yan, LI Xin-yan
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Department of Ultrasound, Maternal and Child Health Care Hospital of Guangxi Zhuang Autonomous Region, Nanning 530000, China
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| Abstract: |
| ［Abstract］ Objective To explore the correlation between the characteristics of contrast-enhanced ultrasonography(CEUS) and molecular biological indicators and axillary lymph node metastasis in breast cancer. Methods Retrospective analysis of the characteristics of CEUS and medical records were performed in 109 female patients with breast cancer. The correlation between the CEUS(including enhancement order, enhancement degree, filling defect, peripheral vascular convergence and enlargement of the enhancement area) and the molecular biological indicators and axillary lymph node metastasis was analyzed. Results Of the 109 patients with a total of 109 lumps, CEUS revealed a filling defect in 68 cases, pathological findings of axillary lymph node metastasis in 64 cases, and Kappa consistency test showed a good consistency between the two examination methods(Kappa=0.732). The sensitivity of filling defect in diagnosis of axillary lymph node metastasis by CEUS was 92.19 % and the specificity was 83.33%. Conclusion The filling defect of CEUS has a certain correlation with axillary lymph node metastasis in breast cancer. It can be used to evaluate the prognosis of breast cancer. |
| Key words: Breast cancer Characteristics of contrast-enhanced ultrasonography Molecular biological indicator Axillary lymph node |
