肿瘤转移相关基因1与妇科恶性肿瘤关系的研究进展

宋　振（综述）; 金　平（审校）

引用本文:	宋　振（综述），金　平（审校）.肿瘤转移相关基因1与妇科恶性肿瘤关系的研究进展[J].中国临床新医学,2022,15(7):662-665.

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肿瘤转移相关基因1与妇科恶性肿瘤关系的研究进展
宋　振（综述），金　平（审校）
518000　广东，南方医科大学附属深圳妇幼保健院妇科

摘要:

［摘要］　肿瘤转移相关基因（MTA）是与肿瘤进展相关的一个基因家族。MTA1是其主要成员之一，在多种肿瘤中异常表达，与肿瘤的侵袭、转移和预后密切相关，具有重要的临床研究价值。该文对MTA1的结构、功能及其在妇科恶性肿瘤中的研究进展作一综述。

关键词: 肿瘤转移相关基因1 组蛋白去乙酰化酶子宫内膜癌宫颈癌卵巢癌

DOI：10.3969/j.issn.1674-3806.2022.07.22

分类号:R 737.31

基金项目:

Research progress on the relationship between tumor metastasis associated gene 1 and gynecological malignant tumors

SONG Zhen, JIN Ping

Department of Gynecology, Shenzhen Maternity and Child Healthcare Hospital Affiliated to Southern Medical University, Guangdong 518000, China

Abstract:

［Abstract］　Tumor metastasis-associated gene(MTA) is a gene family related to tumor progression, of which MTA1 is one of the main members. It is abnormally expressed in a variety of tumors, which is closely related to tumor invasion, metastasis and prognosis, and has important clinical research value. This paper reviews the structure and function of MTA1 and its research progress in gynecological malignant tumors.

Key words: Tumor metastasis-associated gene 1(MTA1) Histone deacetylase Endometrial cancer Cervical cancer Ovarian cancer