| 摘要: |
| ［摘要］ 目的 分析强制诱导性语言疗法联合重复经颅磁刺激（rTMS）对卒中后失语症（PSA）患者失语商（AQ）及语言沟通能力的影响。方法 招募2021年3月至2023年7月陕西省康复医院收治的160例PSA患者作为研究对象。采用随机数字表法将患者分为强制诱导组（80例）和联合组（80例）。强制诱导组采用强制诱导性语言疗法，联合组在强制诱导性语言疗法基础上给予rTMS。两组均连续治疗4周。观察两组患者治疗前后西方失语症成套测验（WAB）评分、AQ指数、功能独立性量表（FIM）中交流亚项评分、日常生活能力交流测验（CADL）评分、蒙特利尔认知评估量表（MoCA）评分变化，比较两组临床疗效。结果 两组治疗后WAB中的自发言语、复述、听理解、命名评分和AQ指数较治疗前提高，且联合组高于强制诱导组，差异有统计学意义（P<0.05）。两组治疗后FIM中的理解、表达评分及CADL评分、MoCA评分较治疗前提高，且联合组高于强制诱导组，差异有统计学意义（P<0.05）。联合组总有效率显著高于强制诱导组（93.75% vs 82.50%； χ2=4.838，P=0.028）。结论 强制诱导性语言疗法联合rTMS治疗PSA疗效显著，可改善患者AQ、语言功能、日常生活交流能力以及认知功能。 |
| 关键词: 强制诱导性语言疗法 卒中后失语症 重复经颅磁刺激 失语商 语言沟通能力 |
| DOI：10.3969/j.issn.1674-3806.2026.03.16 |
| 分类号:R 743.3 |
| 基金项目: |
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| Effects of constraint-induced aphasia therapy combined with repetitive transcranial magnetic stimulation on aphasia quotient and language communication skill in post-stroke aphasia patients |
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WANG Yajie1, JIN Yanchun2, ZHANG Yu3
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1.The First Department of Neurorehabilitation, Shaanxi Rehabilitation Hospital, Xi′an 710065, China; 2.Neurological Regulation Center, Shaanxi Rehabilitation Hospital, Xi′an 710065, China; 3.Department of Neurology, Shaanxi Rehabilitation Hospital, Xi′an 710065, China
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| Abstract: |
| ［Abstract］ Objective To analyze the effects of constraint-induced aphasia therapy(CIAT) combined with repetitive transcranial magnetic stimulation(rTMS) on aphasia quotient(AQ) and language communication skill in post-stroke aphasia(PSA) patients. Methods A total of 160 patients with PSA who were admitted to Shaanxi Rehabilitation Hospital from March 2021 to July 2023 were recruited as the research subjects. The patients were divided into constraint induction group(80 patients) and combination group(80 patients) by using random number table method. The constraint induction group received CIAT. The combination group received rTMS plus CIAT. Both groups were treated continuously for 4 weeks. The changes in Western Aphasia Battery(WAB) scores, aphasia quotient(AQ) index, scores of the communication sub-item in the Functional Independence Measure Scale(FIM), Communication Activities of Daily Living(CADL) scores, and Montreal Cognitive Assessment(MoCA) scores in the patients in the two groups were observed before and after treatment. The clinical efficacy was compared between the two groups. Results After treatment, the scores of spontaneous speech, repetition, listening comprehension and naming in the WAB, and the AQ index in both groups were higher than those before treatment, and the above indicators in the combination group were higher than those in the constraint induction group after treatment, with statistically significant differences(P<0.05). After treatment, the scores of understanding and expression in the FIM, and the CADL scores and MoCA scores in the two groups were higher than those before treatment, and the above indicators in the combination group were higher than those in the constraint induction group after treatment, with statistically significant differences(P<0.05). The total effective rate of the combination group was significantly higher than that of the constraint induction group(93.75 % vs 82.50%; χ2=4.838, P=0.028). Conclusion CIAT combined with rTMS has a significant therapeutic effect on PSA. The combination therapy can improve the patients′ AQ, speech function, daily communication ability, and cognitive function. |
| Key words: Constraint-induced aphasia therapy(CIAT) Post-stroke aphasia(PSA) Repetitive transcranial magnetic stimulation(rTMS) Aphasia quotient(AQ) Language communication skill |
